Browsing College of Pharmacy by Author "Fahmi, Amr Mohamed"
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Warfarin dosing strategies evolution and its progress in the era of precision medicine, a narrative review
Fahmi, Amr Mohamed; Elewa, Hazem; El Jilany, Islam ( Springer , 2022 , Article Review)Background For decades, vitamin K antagonists and specifically warfarin, have been the sole agents used orally to manage thromboembolic conditions, including stroke and venous thromboembolism (VTE). Several factors lead ... -
Warfarin-Rifampin-Gene (WARIF-G) Interaction: A Retrospective, Genetic, Case–Control Study
Salem, Muhammad; El-Bardissy, Ahmed; Elshafei, Mohamed Nabil; Khalil, Ahmed; Mahmoud, Hesham; Fahmi, Amr Mohamed; Kasem, Mohamed; Bader, Loulia; Sherbash, Mohamed; Elawady, Mostafa Ibrahim; Abdalazim, Walaa; Howady, Faraj; Elewa, Hazem... more authors ... less authors ( Wiley-Blackwell , 2023 , Article)Warfarin is extensively metabolized by cytochrome P450 2C9 (CYP2C9). Concomitant use with the potent CYP2C9 inducer, rifampin, requires close monitoring and dosage adjustments. Although, in theory, warfarin dose increase ...