Browsing College of Pharmacy by Title
Now showing items 177-196 of 1261
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Cathepsin B Induced Cardiomyocyte Hypertrophy Requires Activation of the Na+/+ Exchanger Isoform-1
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Background: Progression of the heart to failure is primarily caused due to significant remodeling of both the extracellular matrix (ECM) and subcellular organelles, a hallmark of cardiac hypertrophy (CH). Uncontrolled ECM ... -
Cathine and cathinone disposition kinetics and neurotransmitter profile in several organs of rats exposed to a single dose of Catha edulis (Vahl) Forssk. ex Endl. extract
( Walter de Gruyter , 2023 , Article)Catha edulis (Vahl) Forssk. ex Endl. (Khat) is a stimulant plant that contains cathine and cathinone, which its abuses induce euphoria, alertness, and motor activity. Since the toxicokinetics of these substances remain ... -
CD56 expression in breast cancer induces sensitivity to natural killer-mediated cytotoxicity by enhancing the formation of cytotoxic immunological synapse
( Nature Publishing Group , 2019 , Article)We examined the potential value of the natural killer (NK) cell line; NK-92, as immunotherapy tool for breast cancer (BC) treatment and searched for biomarker(s) of sensitivity to NK-92-mediated cytotoxicity. The cytotoxic ... -
Ceftaroline fosamil for community-acquired pneumonia and skin and skin structure infections: a systematic review
( Springer Netherlands , 2017 , Article)Background Ceftaroline is a parentally administered cephalosporin that has an in vitro expanded spectrum of activity compared with other cephalosporins yet data is conflicting regarding its place in therapy. Aim of the ... -
Cetuximab-conjugated chitosan-pectinate (modified) composite nanoparticles for targeting colon cancer
( Elsevier B.V. , 2019 , Article)In the present study, we successfully developed a cetuximab-conjugated modified citrus pectin-chitosan nanoparticles for targeted delivery of curcumin (Cet-MCPCNPs) for the treatment of colorectal cancer. In vitro analyses ... -
Changes in student perceptions after a semester-long interprofessional education activity in Qatar
( Elsevier , 2016 , Article)Objectives Interprofessional education (IPE) is rapidly becoming integrated into university accreditation standards worldwide. However, the impact of IPE on student learning and practice is largely unknown in the Middle ... -
Characteristics and quality of adverse drug reaction reporting among healthcare providers at Rumailah Hospital in Qatar
( Hamad bin Khalifa University Press (HBKU Press) , 2017 , Article)Introduction: Under-reporting of adverse drug reactions (ADRs) and low-quality reporting are a widespread phenomenon globally.1 There is a need for more insight on the role of pharmacists and other healthcare professionals ... -
Characteristics and quality of adverse drug reaction reporting: a comparison of pharmacists with other healthcare providers at a multi-specialty hospital in Qatar
( Springer International Publishing , 2017 , Article)Objective: Rumailah Hospital (RH) is a multi-specialty hospital with a capacity of 605 beds that serves subacute and long-term patients in Qatar. Since under-reporting and low-quality reporting of adverse drug reactions ... -
Characteristics of drug-related problems and pharmacist’s interventions in hospitalized patients in Thailand: a prospective observational study
( Nature Portfolio , 2022 , Article)Drug-related problems (DRPs) are a major health concern. A better understanding of the characteristics of DRPs throughout the hospital stay may help to tailor pharmaceutical care services (PCS). This study aims to describe ... -
Characteristics of preferred walking patterns in young Qatari adults
( Qatar Foundation , 2016 , Conference Paper)Walking is the most natural and important activity of daily living as it refers to the primary type of terrestrial human locomotion. Analyses of gait patterns typically examine the speed and manner in which people prefer ... -
Characteristics of the clinical pharmacist interventions at the National Center for Cancer Care and Research Hospital in Qatar
( SAGE Publications Ltd , 2023 , Article)Introduction Drug-related problems (DRPs) affect the health outcomes of patients during hospitalization. We sought to analyze the clinical pharmacist-documented interventions among hospitalized patients in the cancer ... -
Characteristics of the clinical pharmacists’ interventions at the main general tertiary care hospital in Qatar
( HBKU Press , 2023 , Article)Medication-related problems (MRPs) are prevalent throughout healthcare systems, whereby pharmacy-based interventions are pivotal to reducing occurrence. In the Middle East, including Qatar, the professional roles of ... -
Characterization and ex vivo evaluation of curcumin nanoethosomes for melanoma treatment
( Taylor & Francis , 2022 , Article)This study aimed at developing curcumin nanoethosomes (Cur-Ets) with superior skin permeation intended for melanoma treatment. Although curcumin is active against many types of skin cancers, a suitable topical formulation ... -
Characterization of cochleate nanoparticles for delivery of the anti-asthma drug beclomethasone dipropionate
( Academic Press , 2020 , Book chapter)Cochleates are an exciting new class of nanocarriers derived from multilamellar liposomes. They have a “cigerette like” structures in which the phospholipid bilayers are joined together by calcium ion bridges making them ... -
Characterizing pharmaceuticals on data exclusivity in Malaysia
( National Institute of Science Communication and Information Resources , 2015 , Article)This study analyses the occurrence and characteristics of pharmaceutical products containing new chemical entities granted data exclusivity in Malaysia since the implementation of the provision in 2011. Data for the drug ... -
Chemically modified mRNA beyond COVID-19: Potential preventive and therapeutic applications for targeting chronic diseases
( Elsevier , 2022 , Article Review)Chemically modified mRNA represents a unique, efficient, and straightforward approach to produce a class of biopharmaceutical agents. It has been already approved as a vaccination-based method for targeting SARS-CoV-2 ... -
Childhood poisoning in Qatar: A call for action
( Society of Hospital Pharmacists of Australia , 2015 , Article)[No abstract available] -
Children's knowledge and beliefs about medicines
( SAGE Publications Inc. , 2015 , Article)Minor illnesses in children are often cured at home with over the counter medicines. Even though there is a wide use of medicines among children, they rarely receive medical advice about their medications from doctors or ... -
Choice of Antimicrobials in Surgical Prophylaxis - Overuse and Surgical Site Infection Outcomes from a Tertiary-Level Care Hospital
( Frontiers Media , 2022 , Article)Background: This study was aimed to describe the choice of Surgical Antimicrobial Prophylaxis at a tertiary-level care hospital in United Arab Emirates. It also associated the choice between two leading antimicrobials for ... -
Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patients
( Frontiers Media S.A. , 2023 , Article)Immune checkpoint inhibitors (ICIs) including anti-PD-1 and anti-PD-L1 antibodies, have significantly changed the treatment outcomes of NSCLC patients with better overall survival. However, 15-40% of the patients still ...