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Elaeagnus angustifolia Plant Extract Inhibits Epithelial-Mesenchymal Transition and Induces Apoptosis via HER2 Inactivation and JNK Pathway in HER2-Positive Breast Cancer Cells
(
MDPI
, 2020 , Article)
Elaeagnus angustifolia (EA) is a medicinal plant used for treating several human diseases in the Middle East. Meanwhile, the outcome of extract on HER2-positive breast cancer remains nascent. Thus, we herein investigated ...
Perspectives of healthcare professionals in Qatar on causes of medication errors: A mixed methods study of safety culture
(
Public Library of Science
, 2018 , Article)
Background There is a lack of robust, rigorous mixed methods studies of patient safety culture generally and notably those which incorporate behavioural theories of change. The study aimed to quantify and explain key aspects ...
Gold-containing compound BDG-I inhibits the growth of A549 lung cancer cells through the deregulation of miRNA expression
(
Elsevier B.V.
, 2018 , Article)
Gold complex bis(diethyldithiocarbamato-gold(I)) bis(diphenylphosphino) methane (BDG-I) is cytotoxic toward different cancer cell lines. We compared the cytotoxic effect of BDG-I with that of cisplatin in the A549 lung ...
Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling
(
hindawi
, 2020 , Article)
Hypertension induces vascular hypertrophy, which changes blood vessels structurally and functionally, leading to reduced tissue perfusion and further hypertension. It is also associated with dysregulated levels of the ...
Exploring the influence of cultural orientations on assessment of communication behaviours during patient-practitioner interactions
(
BioMed Central Ltd.
, 2017 , Article)
Background
Research has shown that patients’ and practitioners’ cultural orientations affect communication behaviors and interpretations in cross-cultural patient-practitioner interactions. Little is known about the effect ...
Effect of SAMe-TT2R2 score and genetic polymorphism on the quality of anticoagulation control in Qatari patients treated with warfarin.
(
Springer Nature
, 2020 , Article)
There is no strong evidence on pharmacogenetics role on the quality of INR control after the initiation phase and on the maintenance of stable INR on the long term as measured by the time in therapeutic range (TTR). The ...
Practice implications of an antimicrobial stewardship intervention in a tertiary care teaching hospital, Qatar
(
World Health Organization
, 2019 , Article)
Background: Antibiotic misuse is a worldwide public health problem and has been associated with increased morbidity, length of hospital stay, mortality, healthcare costs, and most importantly antibiotic resistance. Aims: ...
Impact of a Collaborative Pharmaceutical Care Service Among Patients With Diabetes in an Ambulatory Care Setting in Qatar: A Multiple Time Series Study
(
Elsevier
, 2019 , Article)
Background
Diabetes mellitus is highly prevalent in the Middle East and the burden associated with it is dramatically increasing. Pharmacists working in collaborative healthcare teams have an important role to improve ...
Assessing the effectiveness of a pharmacist-delivered smoking cessation program in the State of Qatar: study protocol for a randomized controlled trial
(
BioMed Central
, 2015 , Article)
Background:
It had been reported that up to 37% of the adult male population smokes cigarettes in Qatar. The
Global Youth Tobacco Survey also stated that 13.4% of male school students aged 13 to 15 years in Qatar smoke ...
Inhibition of p90 Ribosomal S6 Kinase Attenuates Cell Migration and Proliferation of the Human Lung Adenocarcinoma through Phospho-GSK-3b and Osteopontin
(
Hamad bin Khalifa University Press (HBKU Press)
, 2016 , Conference Paper)
Background
Lung cancer is the second most common cancer in both men and women and it is the leading cause of cancer deaths worldwide. Lung cancer can be divided into two broad categories: non-small cell lung cancer ...