Search
Now showing items 21-30 of 46
Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart
(
Elsevier Ireland Ltd.
, 2014 , Article)
Mercury exposure is associated with increased risk of cardiovascular disease and profound cardiotoxicity. However, the correlation between Hg2+-mediated toxicity and alteration in cardiac cytochrome P450s (Cyp) and their ...
Cost effectiveness of caspofungin vs. voriconazole for empiric therapy in Turkey
(
Blackwell Publishing Ltd
, 2014 , Article)
Invasive fungal infections from febrile neutropenia are associated with significant cost and mortality. The mainstay of treatment has been liposomal amphotericin B, however, echinocandins and azoles have shown promise as ...
Editorial: What Are the Challenges in Conducting Cost-of-Illness Studies?
(
Elsevier Inc.
, 2014 , Article)
Suitability of digoxin as a P-glycoprotein probe: Implications of other transporters on sensitivity and specificity
(
John Wiley & Sons Ltd.
, 2014 , Article)
The study of transporter-mediated drug–drug interactions (DDI) requires use of appropriate probes to reflect transporter function. Digoxin is often used as a probe in DDI studies involving P-glycoprotein (P-gp) and is ...
What Are the Challenges in Conducting Cost-of-Illness Studies?
(
Elsevier Inc.
, 2014 , Article)
[No abstract available]
Drug-related problems identified by pharmacists conducting medication use reviews at a primary health center in Qatar
(
Kluwer Academic Publishers
, 2014 , Article)
Background: Medication use review (MUR) is increasingly being recognized globally as a routine strategy performed by pharmacists to optimize the therapeutic outcomes of long-term medications. MUR services are not commonly ...
Microbial production of 1α-hydroxyvitamin D3 from vitamin D3
(
Taylor and Francis Ltd.
, 2014 , Article)
The microbial transformation of vitamin D3 (1) by the fungi Candida maltosa R42 and Botrytis allii NRRL 2502 was investigated. Incubation of compound 1 with C. maltosa R42 and B. allii NRRL 2502 produced the same three ...
Comparability of Interview and Self-Administration of the Functional Assessment of Chronic Illness Therapy-Tuberculosis (Facit-Tb) Instrument in Iraqi Pulmonary Tuberculosis Patients
(
Elsevier
, 2014 , Article)
Objectives
To investigate the extent to which two different modes of administration (interview by a trained interviewer versus self-administration) yielded a comparable estimate of health-related quality of life (HRQL) ...
Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms
(
Elsevier Inc.
, 2014 , Article)
Activation of the aryl hydrocarbon receptor (AhR) ultimately leads to the induction of the carcinogen-activating enzyme cytochrome P450 1A1 (CYP1A1), and activation of the nuclear factor-erythroid 2 p45-related factor 2 ...
Systematic review of factors affecting pharmaceutical expenditures
(
Elsevier Ireland Ltd
, 2014 , Article Review)
Objective: To systematically identify the main factors contributing to the increase in pharmaceutical expenditures. Methods: A systematic search of published studies was conducted utilising major widely used electronic ...