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Enhancement in Oral Absorption of Ceftriaxone by Highly Functionalized Magnetic Iron Oxide Nanoparticles.
(
MDPI
, 2020 , Article)
The present study aims at the development, characterization, biocompatibility investigation and oral bioavailability evaluation of ceftriaxone (CFT)-loaded N'-methacryloylisonicotinohydrazide (MIH)-functionalized magnetic ...
Assessment of the attitude, awareness and practice of periprocedural warfarin management among health care professional in Qatar. A cross sectional survey
(
Springer
, 2020 , Article)
It is estimated that 10–15% of oral anticoagulant (OAC) patients, would need to hold their OAC for scheduled surgery. Especially for warfarin, this process is complex and requires multi-layer risk assessment and decisions ...
Qatar-Sustaining Interprofessional Collaboration in Collaborative Partnership with Other Universities
(
Springer
, 2020 , Article)
The State of Qatar, an oil and gas rich nation, is a sovereign Arab state situated in the Arabian Gulf Region of the Middle East. The country’s population has grown significantly in the last twenty years, due to the large ...
Anti-hypertrophic effect of Na+/H+ exchanger-1 inhibition is mediated by reduced cathepsin B
(
Elsevier
, 2020 , Article)
Previous studies have established the role of Na+/H+ exchanger isoform-1 (NHE1) and cathepsin B (Cat B) in the development of cardiomyocyte hypertrophy (CH). Both NHE1 and Cat B are activated under acidic conditions ...
Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation
(
Elsevier
, 2020 , Article)
AimThe aim of this study was to improve the therapeutic index of chemotherapeutic drugs on glioblastoma cells through an improved co-drug delivery system. Materials and methodsMethotrexate (MTX) and paclitaxel (PTX) were ...
Phenethyisoquinoline alkaloids from the leaves of Androcymbium palaestinum
(
Elsevier
, 2020 , Article)
Thirteen compounds were isolated from the methanolic extract of the leaves of Androcymbium palaestinum Baker (Colchicaceae). Of these, three were new, two were new natural products, and eight were known. The new isolated ...
Pharmacokinetics and tissue distribution of an orally administered mucoadhesive chitosan-coated amphotericin B-Loaded nanostructured lipid carrier (NLC) in rats
(
Taylor and Francis Inc.
, 2020 , Article)
Oral delivery of amphotericin B (AmpB) is desirable because it provides a more patient-friendly mode of administration compared to the current delivery approach akin with the marketed AmpB formulations. The goal of the ...
Awareness of the risk factors for heart attack among the general public in pahang, malaysia: A cross-sectional study
(
Dove Medical Press
, 2020 , Article)
Background: Cardiovascular disease is a leading nationwide cause of morbidity and mortality. Public awareness of risk factors for heart attacks is thought to impact the burden of disease, prevention, and timely management. ...
An exploratory analysis of the portrayal of mental illness in Qatar’s newspapers
(
Dove Medical Press
, 2020 , Article)
Background: Concerns have been raised about the role of the media influencing the public’s understanding of mental illness. Aim: This study explored the extent and nature of mental health coverage in Qatar’s newspapers. A ...
Adipose tissue immunomodulation: A novel therapeutic approach in cardiovascular and metabolic diseases
(
Frontiers Media
, 2020 , Article)
Adipose tissue is a critical regulator of systemic metabolism and bodily homeostasis as it secretes a myriad of adipokines, including inflammatory and anti-inflammatory cytokines. As the main storage pool of lipids, ...