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AMP-activated protein kinase as a drug target in chronic kidney disease
(
Bentham Science Publishers B.V.
, 2018 , Article Review)
Background: Chronic kidney disease (CKD) is a condition increasingly affecting millions of individuals worldwide and is ranked as the ninth leading cause of death in the United States. AMP-activated protein kinase (AMPK) ...
Cisplatin based therapy: The role of the mitogen activated protein kinase signaling pathway
(
BioMed Central Ltd.
, 2018 , Article Review)
Cisplatin is a widely used chemotherapeutic agent for treatment of various cancers. However, treatment with cisplatin is associated with drug resistance and several adverse side effects such as nephrotoxicity, reduced ...
Review of National and International Accreditation of Pharmacy Programs in the Gulf Cooperation Council Countries.
(
Aacp American Association
, 2018 , Article Review)
To compare the different philosophies, emphases and processes of national and international accreditation paths available to pharmacy programs in Gulf Cooperation Council (GCC) countries. To identify engagement of GCC ...
A Review of the Clinical Pharmacokinetics and Pharmacodynamics of Isavuconazole
(
Springer-Verlag France
, 2018 , Article Review)
Invasive fungal infections are a major cause of morbidity and mortality, especially for immunocompromised patients. Treatment options are few and most are limited by safety and formulation concerns. Isavuconazole is a new ...
Clinical Pharmacokinetics and Drug Interactions of Doravirine
(
Springer-Verlag France
, 2018 , Article Review)
Doravirine is a new HIV-1 non-nucleoside reverse transcriptase inhibitor that has demonstrated a good efficacy and safety profile in clinical trials. It has a therapeutic profile that makes it an attractive option for ...
Direct Oral Anticoagulant Use in Atypical Thrombosis-Related Conditions
(
SAGE Publications Inc.
, 2018 , Article Review)
Objective: To review the published literature for evidence of the efficacy and safety of direct oral anticoagulants (DOACs) when used in the management of atypical thrombosis-related conditions. Data Sources: A comprehensive ...
Efficacy and safety of laxatives for chronic constipation in long-term care settings: A systematic review
(
Blackwell Publishing Ltd
, 2018 , Article Review)
What is known and objective: Constipation is a common disorder among long-term care (LTC) patients due to several factors. However, there are no systematic reviews investigating the use of laxatives for chronic constipation ...
Rational development of nanomedicines for molecular targeting in periodontal disease
(
Elsevier Ltd
, 2018 , Article Review)
Recent advances in understanding the etiology and pathogenesis of periodontal disease and polymicrobial synergy in the dysbiotic oral microbial community endorsed novel therapeutic targets and assured further improvement ...
Stigma associated with mental illness and its treatment in the Arab culture: A systematic review
(
SAGE Publications Ltd
, 2018 , Article Review)
Background: Mental health has not had the same public profile as physical health. This has contributed to the stigma associated with mental illness and to its treatments. Research investigating how the traditions and values ...
Stakeholders' views and experiences of pharmacist prescribing: a systematic review
(
Blackwell Publishing Ltd
, 2018 , Article Review)
Aims
The aims of this systematic review were to: (1) critically appraise, synthesize and present the available evidence on the views and experiences of stakeholders on pharmacist prescribing and; (2) present the perceived ...