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Metformin Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro
(
Wiley Periodicals, Inc
, 2017 , Article)
Proteinuria (albuminuria) plays a crucial role in the etiology of chronic kidney disease (CKD) via alteration of multiple signaling pathways and cellular process in renal cells. The objectives of this study are to investigate ...
Structure–activity relationship of piperine and its synthetic amide analogs for therapeutic potential to prevent experimentally induced ER stress in vitro
(
Springer Netherlands
, 2017 , Article)
Endoplasmic reticulum (ER) is the key organelle involved in protein folding and maturation. Emerging studies implicate the role of ER stress in the development of chronic kidney disease. Thus, there is an urgent need for ...
Nephroprotective Effects of Metformin in Diabetic Nephropathy
(
Wiley
, 2017 , Article)
Metformin, a well-known anti-diabetic agent, is very effective in lowering blood glucose in patients with type 2 diabetes with minimal side-effects. Metformin is also being recommended in the treatment of obesity and ...
Aldose Reductase as a Drug Target for Treatment of Diabetic Nephropathy: Promises and Challenges.
(
Bentham Science Publishers
, 2017 , Article)
Diabetic nephropathy (DN) is one of the most serious microvascular complications of diabetes mellitus and the leading cause of end stage renal disease. One of the key pathways activated in DN is the polyol pathway, in which ...
Effectiveness of a pharmacist-delivered smoking cessation program in the State of Qatar: a randomized controlled trial
(
BioMed Central
, 2017 , Article)
Background: Cigarette smoking is one of the major preventable causes of death and diseases in Qatar. The study objective was to test the effect of a structured smoking cessation program delivered by trained pharmacists on ...
Evaluation of the general public's knowledge, views and practices relating to appropriate antibiotic use in Qatar
(
Wiley-Blackwell Publishing Ltd
, 2017 , Article)
Objective: Studies completed internationally have demonstrated an alarming number of patients believed antibiotics are indicated in the treatment of viral infections and other self-limited illnesses. Evaluation of patient ...
Strategies to Optimize Dual Antiplatelet Therapy after Coronary Artery Stenting in Acute Coronary Syndrome
(
SAGE Publications Ltd
, 2017 , Article)
The use of aspirin and a P2Y12 receptor antagonist as dual antiplatelet therapy (DAPT) has become the treatment of choice in patients with acute coronary syndrome (ACS) and percutaneous coronary intervention to prevent ...
Utilization of simulated patients to assess diabetes and asthma counseling practices among community pharmacists in Qatar
(
Springer Netherlands
, 2017 , Article)
Background Patient counseling is one of the most important services a pharmacist can provide to patients. Studies have shown that counseling provided by pharmacists may prevent medication related problems and improve ...
Readability and Comprehensibility of Patient Information Leaflets for Antidiabetic Medications in Qatar
(
SAGE Publications Inc.
, 2017 , Article)
Background:The readability and comprehensibility of the patient information leaflets (PILs) provided with antidiabetic medications are of questionable standards; this issue negatively affects adherence to drug therapy, ...
An evaluation of the translation of continuing education into diabetes public health care by pharmacists
(
Springer Netherlands
, 2017 , Article)
Background Pharmacists are assuming greater public health roles and partaking in continuing education to advance knowledge and skills necessary for the provision of this patient care. Objective We sought to determine what ...