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Now showing items 21-30 of 221
Epinephrine in anaphylaxis: Preclinical study of pharmacokinetics after sublingual administration of taste-masked tablets for potential pediatric use
(
MDPI AG
, 2018 , Article)
Epinephrine is a life-saving treatment in anaphylaxis. In community settings, a first-aid dose of epinephrine is injected from an auto-injector (EAI). Needle phobia highly contributes to EAI underuse, leading to ...
Endoplasmic Reticulum (ER) Stress-Generated Extracellular Vesicles (Microparticles) Self-Perpetuate ER Stress and Mediate Endothelial Cell Dysfunction Independently of Cell Survival.
(
Frontiers Media
, 2020 , Article)
Circulating extracellular vesicles (EVs) are recognized as biomarkers and effectors of endothelial dysfunction, the initiating step of cardiovascular abnormalities. Among these EVs, microparticles (MPs) are vesicles directly ...
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells.
(
Dove Medical Press
, 2020 , Article)
Venetoclax (VCX) is a selective BCL-2 inhibitor approved for the treatment of leukemia and lymphoma. However, the mechanisms of anti-cancer effect of VCX either as a monotherapy or in combination with other chemotherapeutic ...
Phloretin attenuates STAT-3 activity and overcomes sorafenib resistance targeting SHP-1-mediated inhibition of STAT3 and Akt/VEGFR2 pathway in hepatocellular carcinoma
(
BioMed Central Ltd.
, 2019 , Article)
Background: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy. Phloretin (PH) possesses anticancer, antitumor, and hepatoprotective effects, however, the effects and potential mechanisms of phloretin ...
Healthcare practitioners’ views of their role in addressing the medical comorbidites of people with mental illness
(
Fortune Journals
, 2020 , Article)
Objectives: To explore the views and experiences of different healthcare professionals in Qatar about their role addressing the medical comorbidities of people with serious mental illness (SMI).
Subjects and Methods: ...
Adult Learning Theories in Context: A Quick Guide for Healthcare Professional Educators.
(
SAGE Publications
, 2018 , Article)
Adult learning theories play a pivotal role in the design and implementation of education programs, including healthcare professional programs. There is a variation in the use of theories in healthcare professional education ...
A service evaluation and stakeholder perspectives of an innovative digital minor illness referral service from NHS 111 to community pharmacy.
(
Public Library of Science
, 2020 , Article)
The management of minor conditions represents a significant burden for urgent and emergency care services and reduces the capacity to provide specialist care for higher acuity healthcare need. A pilot Digital Minor Illness ...
Ibrutinib-associated sever skin toxicity: A case of multiple inflamed skin lesions and cellulitis in a 68-year-old male patient with relapsed chronic lymphocytic leukemia Case report and literature review
(
SAGE Publications Ltd
, 2019 , Article)
Introduction: Ibrutinib is an oral inhibitor of Bruton's tyrosine kinase that is used for a variety of B cell hematological malignancies. Skin and subcutaneous tissue manifestations have been reported and were witnessed ...
Perception of community pharmacy personnel towards patient counseling and continuing pharmacy education programs in Aden, Yemen
(
Journal of Clinical and Diagnostic Research
, 2018 , Article)
© 2018, Journal of Clinical and Diagnostic Research. All rights reserved. Introduction: Patient counseling is a major component of pharmaceutical care, especially in community pharmacy settings. However, most community ...
There Is Selective Increase in Pro-thrombotic Circulating Extracellular Vesicles in Acute Ischemic Stroke and Transient Ischemic Attack: A Study of Patients From the Middle East and Southeast Asia.
(
Frontiers Media
, 2019 , Article)
Stroke attacks were found to be present at a younger age in patients from Southeast Asia (SE) and the Middle East (ME) resident in the state of Qatar. Extracellular vesicles (EVs), which are small membrane vesicles with ...