Search
Now showing items 511-520 of 724
Improving the quality of publications in and advancing the paradigms of clinical and social pharmacy practice research: The Granada Statements
(
European Association of Hospital Pharmacists (EAHP)
, 2023 , Article)
Pharmacy and pharmaceutical sciences embrace a series of different disciplines. Pharmacy practice has been defined as € the scientific discipline that studies the different aspects of the practice of pharmacy and its impact ...
An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels
(
Thieme
, 2022 , Article)
This international guideline proposes improving clozapine package inserts worldwide by using ancestry-based dosing and titration. Adverse drug reaction (ADR) databases suggest that clozapine is the third most toxic drug ...
Pharmacies in the Airport Ecosystem and How They Serve Travelers' Health and Medicines Need: Findings and Implications for the Future.
(
Dove Press
, 2022 , Article)
Pharmacists at airport pharmacies could offer essential health services for air travelers. Consequently, this study aimed to explore the type of professional services, the types of medicines at airport pharmacies and ...
The role of amyloids in Alzheimer's and Parkinson's diseases
(
Elsevier
, 2021 , Article)
With varying clinical symptoms, most neurodegenerative diseases are associated with abnormal loss of neurons. They share the same common pathogenic mechanisms involving misfolding and aggregation, and these visible aggregates ...
Improved bioavailability of poorly soluble drugs through gastrointestinal muco-adhesion of lipid nanoparticles
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2021 , Article)
Gastrointestinal absorption remains indispensable in the systemic delivery of most drugs, even though it presents several challenges that, paradoxically, may also provide opportunities that can be exploited to achieve ...
Clinical and humanistic outcomes of community pharmacy‐based healthcare interventions regarding medication use in older adults: A systematic review and meta‐analysis
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2021 , Article)
This review and meta‐analysis aimed to determine the clinical and humanistic outcomes of community pharmacy‐based interventions on medication‐related problems of older adults at the primary care level. We identified ...
Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Spliceosome
(
Frontiers Media S.A.
, 2021 , Article)
Background: Tumor glycolysis is a target for cancer chemotherapy. Methylglyoxal (MG) is a reactive metabolite formed mainly as a by-product in anaerobic glycolysis, metabolized by glyoxalase 1 (Glo1) of the glyoxalase ...
Beta-caryophyllene exhibits anti-proliferative effects through apoptosis induction and cell cycle modulation in multiple myeloma cells
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2021 , Article)
Cannabinoid receptors, which are widely distributed in the body, have been considered as possible pharmacological targets for the management of several tumors. Cannabinoid type 2 receptors (CB2Rs) belong to the G protein-coupled ...
Mechanisms of amyloid proteins aggregation and their inhibition by antibodies, small molecule inhibitors, nano-particles and nano-bodies
(
Elsevier
, 2021 , Article)
Protein misfolding and aggregation can be induced by a wide variety of factors, such as dominant disease-associated mutations, changes in the environmental conditions (pH, temperature, ionic strength, protein concentration, ...
Long-acting injectable antipsychotics: A systematic review of their non-systemic adverse effect profile
(
Dove Medical Press
, 2021 , Article)
Introduction: Long acting injectable (LAI) antipsychotics are commonly used in the treatment of schizophrenia to improve adherence and clinical outcomes. Concerns have been reported in relation to their non-systemic or ...