Browsing Biomedical Research Center Research by Author "n 85321552"
Now showing items 1-4 of 4
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Assessment of calcified aortic valve leaflet deformations and blood flow dynamics using fluid-structure interaction modeling
Amindari, Armin; Saltik, Levent; Kirkkopru, Kadir; Yacoub, Magdi; Yalcin, Huseyin C. ( Elsevier , 2017 , Article)Aortic valve diseases are among the most common cardiovascular defects. Since a non-functioning valve results in disturbed blood flow conditions, the diagnosis of such defects is based on identification of stenosis via ... -
Heart function and hemodynamic analysis for zebrafish embryos
Yalcin, Huseyin C.; Amindari, Armin; Butcher, Jonathan T.; Althani, Asma; Yacoub, Magdi ( John Wiley and Sons Inc. , 2017 , Article Review)The Zebrafish has emerged to become a powerful vertebrate animal model for cardiovascular research in recent years. Its advantages include easy genetic manipulation, transparency, small size, low cost, and the ability to ... -
Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening.
Shurbaji, Samar; El-Sherbiny, Ibrahim M; Alser, Maha; Ali, Isra H; Kordi, Haya; Al-Sadi, Ameena; Popelka, Anton; Benslimane, Fatiha; Yacoub, Magdi; Yalcin, Huseyin C... more authors ... less authors ( Frontiers , 2021 , Article)Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung condition. It is characterized by disruption of gas exchange inside the alveoli, accumulation of protein edema, and an increase in lung stiffness. ... -
Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
Da’as, Sahar Isa; Hasan, Waseem; Salem, Rola; Younes, Nadine; Abdelrahman, Doua; Mohamed, Iman A.; Aldaalis, Arwa; Temanni, Ramzi; Mathew, Lisa Sara; Lorenz, Stephan; Yacoub, Magdi; Nomikos, Michail; Nasrallah, Gheyath K.; Fakhro, Khalid A.... more authors ... less authors ( MDPI , 2022 , Article)Variants in cardiac myosin-binding protein C (cMyBP-C) are the leading cause of inherited hypertrophic cardiomyopathy (HCM), demonstrating the key role that cMyBP-C plays in the heart’s contractile machinery. To investigate ...