Search
Now showing items 1-10 of 76
Nanomedicine for Cancer.
(
Bentham Science Publishers
, 2022 , Article)
Over the past decades, oncology has occupied the lion’s share of all nanomedical applications [1-3]. In 2020, up to 65% of the clinical trials involving nanomaterials were
attending to cancer therapeutics and diagnostics ...
Long-term COVID-19 booster effectiveness by infection history and clinical vulnerability and immune imprinting: a retrospective population-based cohort study
(
Elsevier
, 2023 , Article)
BackgroundLong-term effectiveness of COVID-19 mRNA boosters in populations with different previous infection histories and clinical vulnerability profiles is inadequately understood. We aimed to investigate the effectiveness ...
Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar
(
BMJ Publishing Group
, 2023 , Article)
Objective To assess the evolution of COVID-19 severity and fatality in a unique setting that consistently applied, throughout the pandemic, rigorous and standardised criteria for defining severe COVID-19 outcomes.
Methods ...
Prevalence of hepatitis B and C viruses among migrant workers in Qatar.
(
Springer Nature
, 2024 , Article)
Limited data exist on viral hepatitis among migrant populations. This study investigated the prevalence of current hepatitis B virus (HBV) infection and lifetime hepatitis C virus (HCV) infection among Qatar's migrant craft ...
Estimating protection afforded by prior infection in preventing reinfection: Applying the test-negative study design.
(
Oxford University Press
, 2023 , Article)
The COVID-19 pandemic has highlighted the need to use infection testing databases to rapidly estimate effectiveness of prior infection in preventing reinfection ($P{E}_S$) by novel SARS-CoV-2 variants. Mathematical modeling ...
Evaluation of the mindray CL900i CLIA HIV Ag/Ab combo assay for sensitive and specific HIV screening compared to established methods.
(
Springer Nature
, 2024 , Article)
Architect-HIV Ag/Ab combo chemiluminescence assay is globally recognized for its sensitivity but has a notable false-positive rate. In this study, we aim to evaluate the performance of a new cost-effective screening ...
A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
(
Elsevier
, 2025 , Article)
Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows ...
Protection conferred by SARS-CoV-2 infection across a spectrum of reinfection symptoms and severities
(
BMJ Publishing Group
, 2025 , Article)
Background SARS-CoV-2 infection is associated with protection against reinfection. This study analysed this protection across different reinfection symptoms and severities, comparing the preomicron and omicron eras. Methods ...
Assessing healthy vaccinee effect in COVID-19 vaccine effectiveness studies: a national cohort study in Qatar.
(
National Center for Biotechnology Information
, 2025 , Article)
This study investigated the presence of the healthy vaccinee effect-the imbalance in health status between vaccinated and unvaccinated individuals-in two rigorously conducted COVID-19 vaccine effectiveness studies involving ...
Viruses and Autoimmunity: A Review on the Potential Interaction and Molecular Mechanisms.
(
MDPI
, 2019 , Article)
For a long time, viruses have been shown to modify the clinical picture of several autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren's syndrome ...









