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Pre-fusion structure of a human coronavirus spike protein
(
Nature Publishing Group
, 2015 , Article)
HKU1 is a human betacoronavirus that causes mild yet prevalent
respiratory disease1, and is related to the zoonotic SARS2 and
MERS3 betacoronaviruses, which have high fatality rates and
pandemic potential. Cell tropism ...
Human olfactory bulb neural stem cells mitigate movement disorders in a rat model of Parkinson's disease.
(
Wiley
, 2015 , Article)
Parkinson's disease (PD) is a neurological disorder characterized by the loss of midbrain dopaminergic (DA) neurons. Neural stem cells (NSCs) are multipotent stem cells that are capable of differentiating into different ...
Human Olfactory Bulb Neural Stem Cells Expressing hNGF Restore Cognitive Deficit in Alzheimer's Disease Rat Model
(
Wiley
, 2015 , Article)
In this study, we aim to demonstrate the fate of allogenic adult human olfactory bulb neural stem/progenitor cells (OBNSC/NPCs)
transplanted into the rat hippocampus treated with ibotenic acid (IBO), a neurotoxicant ...
Detection and Phylogenetic Analysis of Human Pegivirus (GBV-C) Among Blood Donors and Patients Infected With Hepatitis B Virus (HBV) in Qatar
(
Wiley
, 2015 , Article)
Human Pegivirus (HPgV), formerly GB virus-C/
Hepatitis G virus (GBV-C/HGV), collectively
known as GBV-C, is widely spread and has
been reported to be associated with non-A–E
hepatitis. To our knowledge, no previous ...
Detection and Genotyping of Torque Teno Virus (TTV) in Healthy Blood Donors and Patients Infected With HBV or HCV in Qatar
(
Wiley Periodicals, Inc
, 2015 , Article)
Torque Teno virus (TTV) has been associated
with non A–G hepatitis. The goal of this study
was to estimate the infection rates and genotypic
characteristics of TTV in the State of Qatar.
A total of 644 blood samples ...
First Study in Qatar to Reveal High Legionella Count in Cooling Towers
(
Oxford University Press - ASCP
, 2015 , Article)
Legionella is an intracellular bacterium that can cause a severe communityacquired
and nosocomial
pneumonia, known as legionnaire disease (LD). The bacterium thrives in freshwater environments,
including manmade
water ...
A YEAST TWO-HYBRID SCREEN REVEALS A STRONG INTERACTION BETWEEN THE LEGIONELLA CHAPERONIN Hsp60 AND THE HOST CELL SMALL HEAT SHOCK PROTEIN Hsp10
(
Akadémiai Kiadó
, 2015 , Article)
L. pneumophila is an intracellular bacterium that replicates inside a membrane-
bound vacuole called Legionella-containing vacuole (LCV), where it plentifully
liberates its HtpB chaperonin. From LCV, HtpB reaches the ...
E5 and E6/E7 of high-risk HPVs cooperate to enhance cancer progression through EMT initiation
(
Taylor & Francis
, 2015 , Article)
It is estimated that 10–20% of human carcinogenesis is linked to virus infection including papillomaviruses (HPVs). Moreover, since metastatic cancer disease is a major cause of morbidity and mortality in cancer patients, ...
E-cadherin/catenin complex modulations in human oral cancer
(
Springer Netherlands
, 2015 , Book chapter)
Oral cancer is a common neoplasm in both male and female worldwide; the incidence and mortality of this cancer have increased over the past decades. Cancer metastasis is a major cause of morbidity and mortality in oral ...
Pseudomonas aeruginosa: arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies.
(
Future Medicine
, 2015 , Article)
Antimicrobial resistance is one of the most serious public health issues facing humans since the discovery of antimicrobial agents. The frequent, prolonged, and uncontrolled use of antimicrobial agents are major factors ...