Browsing College of Health Sciences by Author "Modjtahedi, Helmout"
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Description of PTPRG genetic variants identified in a cohort of Chronic Myeloid Leukemia patients and their ability to influence response to Tyrosine kinase Inhibitors
Mohamed A., Ismail; Nasrallah, Gheyath K.; Monne, Maria; AlSayab, Ali; Yassin, Mohamed A.; Varadharaj, Govindarajulu; Younes, Salma; Sorio, Claudio; Cook, Richard; Modjtahedi, Helmout; Al-Dewik, Nader I.... more authors ... less authors ( Elsevier , 2022 , Article)Tyrosine kinase inhibitors (TKIs) have remarkably transformed Ph+ chronic myeloid leukemia (CML) management; however, TKI resistance remains a major clinical challenge. Mutations in BCR-ABL1 are well studied but fail to ...