Browsing College of Health Sciences by Author "Alwakeel, Mariam"
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Association between Genetic Variants of GC Gene at 4q13.3 and Vitamin D Concentrations in Adult Females
sharif, Elham; Rizk, Nasser; Thakur, Hajera; Kurdi, Tasnim; Alwakeel, Mariam ( Longdom , 2019 , Article)Background: Vitamin D binding protein, encoded by the GC gene (on 4q13.3), plays an important role in transporting vitamin D. Several Genome-Wide Association Studies (GWASs) have established a significant association ... -
Neutrophil Gelatinase Associated Lipocalin: Is not an Early Marker Inductor for Diabetic Nephropathy in Qatari Population
Sharif, Elham; Alwakeel, Mariam ( BJSTR , 2019 , Article)Background: The WHO Global Report on Diabetes (2016) showed that the number of diabetic patients quadrupled between 1980 and 2016, while causing the death of 1.5 million people. While the global prevalence of diabetes ... -
New markers for the detection of polycystic ovary syndrome
Sharif, Elham; Alwakeel, Mariam ( MedCrave Group , 2019 , Article)Polycystic Ovary Syndrome (PCOS) is a highly prevalent, complex genetic disorder of the endocrine system in women. Alterations that occur in women with PCOS can be due to several predisposing factors; among these contributors ... -
Obesity is associated with the upregulation of TLR4 protein but not associated with polymorphisms of TLR4D299G TLR4T399I
Alwakeel, Mariam; Galash, Afnan O.; Saleh, Amina; Alkhanji, FadelMooza; Rizk, Nasser M. ( Hamad bin Khalifa University Press (HBKU Press) , 2018 , Conference Paper)Title: Obesity is associated with the upregulation of TLR4 protein but not associated with polymorphisms of TLR4D299G TLR4T399I.Background: Toll-like-receptor 4 (TLR4) is a pathogen-specific receptor, expressed in white ... -
The role of polymorphisms in vitamin d-related genes in response to vitamin d supplementation
Tomei, Sara; Singh, Parul; Mathew, Rebecca; Mattei, Valentina; Garand, Mathieu; Alwakeel, Mariam; Sharif, Elham; Khodor, Souhaila Al... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Background. Vitamin D deficiency represents a major healthcare problem. Vitamin D status is influenced by genetic and environmental determinants. Several observational studies have evaluated the association of single-nucleotide ... -
The potential role of vitamin D supplementation as a gut microbiota modifier in healthy individuals
Singh, Parul; Rawat, Arun; Alwakeel, Mariam; Sharif, Elham; Al Khodor, Souhaila ( Nature Research , 2020 , Article)Vitamin D deficiency affects approximately 80% of individuals in some countries and has been linked with gut dysbiosis and inflammation. While the benefits of vitamin D supplementation on the gut microbiota have been studied ...