Browsing College of Health Sciences by Title
Now showing items 694-713 of 1600
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Funding sources and costs to deliver cardiac rehabilitation around the globe: Drivers and barriers.
( Elsevier , 2018 , Article)Cardiac rehabilitation (CR) reach is minimal globally, primarily due to financial factors. This study characterized CR funding sources, cost to patients to participate, cost to programs to serve patients, and the drivers ... -
Gene Expression Profiling and Protein Analysis Reveal Suppression of the C-Myc Oncogene and Inhibition JAK/STAT and PI3K/AKT/mTOR Signaling by Thymoquinone in Acute Myeloid Leukemia Cells
( MDPI , 2022 , Article)Overexpression of c-Myc plays an essential role in leukemogenesis and drug resistance, making c-Myc an attractive target for cancer therapy. However, targeting c-Myc directly is impossible, and c-Myc upstream regulator ... -
Gene Expression Profiling of Embryonic Human Neural Stem Cells and Dopaminergic Neurons from Adult Human Substantia Nigra
( Public Library of Science , 2011 , Article)Neural stem cells (NSC) with self-renewal and multipotent properties serve as an ideal cell source for transplantation to treat neurodegenerative insults such as Parkinson’s disease. We used Agilent’s and Illumina Whole ... -
Gene Expression Profiling of Embryonic Human Neural Stem Cells and Dopaminergic Neurons from Adult Human Substantia Nigra
( Hamad bin Khalifa University Press (HBKU Press) , 2012 , Conference Paper)Neural stem cells (NSC) with self-renewal and multipotent properties serve as an ideal cell source for transplantation to treat neurodegenerative insults such as Parkinson's disease. We used Agilent's and Illumina Whole ... -
General practitioner use of a C-reactive protein point-of-care test to help target antibiotic prescribing in patients with acute exacerbations of chronic obstructive pulmonary disease (the PACE study): study protocol for a randomised controlled trial.
( BioMed Central , 2017 , Article)Most patients presenting with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in primary care are prescribed an antibiotic, which may not always be appropriate and may cause harm. C-reactive protein ... -
The genetic basis and the diagnostic yield of genetic testing related to nonsyndromic hearing loss in Qatar
( Springer Nature , 2024 , Article)Hearing loss is the most predominant sensory defect occurring in pediatrics, of which, 66% cases are attributed to genetic factors. The prevalence of hereditary hearing loss increases in consanguineous populations, and the ... -
The Genetic Control of the Rheumatic Heart: Closing the Genotype-Phenotype Gap
( Frontiers Media , 2021 , Article Review)Rheumatic heart disease (RHD) is a heritable inflammatory condition characterized by carditis, arthritis, and systemic disease. Although remaining neglected, the last 3 years has seen some promising advances in RHD research. ... -
Genetic Diversity and Prevalence of in Qatar.
( Frontiers Media , 2021 , Article)is a common human intestinal parasite worldwide, and the causative agent of diarrhea, with the severity of disease ranging from asymptomatic to intense and debilitating infection. is known to consist of eight genetically ... -
The genetic elucidation of monogenic obesity in the Arab world: a systematic review
( J Pediatr Endocrinol Metab , 2022 , Article)Background: Investigation of monogenic obesity (MO), a rare condition caused by a single gene variant(s), especially in consanguineous populations, is a powerful approach for obtaining novel insights into the genetic ... -
Genetic Epidemiology of Beta-Thalassemia in the Maldives: 23 years of a Beta-Thalassemia Screening Program.
( Elsevier , 2020 , Article)The Maldives is an archipelago of 407,660 people according to population census of 2014, made up of 20 atolls, which has one of the highest prevalence of β-thalassemia worldwide. However, there is a dearth of studies related ... -
Genetic Epidemiology of Glucose-6-Dehydrogenase Deficiency in the Arab World
( Nature Publishing Group , 2016 , Article)A systematic search was implemented using four literature databases (PubMed, Embase, Science Direct and Web of Science) to capture all the causative mutations of Glucose-6-phosphate dehydrogenase (G6PD) deficiency (G6PDD) ... -
Genetic Epidemiology of Hearing Loss in the 22 Arab Countries: A Systematic Review
( Wolters Kluwer Health , 2019 , Article)Hearing loss (HL) is a heterogeneous condition that causes partial or complete hearing impairment. Hundreds of variants in more than 60 genes have been reported to be associated with Hereditary HL (HHL). The HHL prevalence ... -
Genetic epidemiology of male infertility (MI) in Arabs: a systematic review
( CSIRO , 2022 , Article Review)Although Male Infertility (MI) in Arabs is fairly common, there is a dearth in published reports of genetic epidemiology of MI among Arabs. This study aimed to review the existing literature reporting the variants that are ... -
Genetic epidemiology of ovarian cancer in the 22 Arab countries: A systematic review.
( Elsevier , 2019 , Article)Ovarian cancer (OC) is a common disease among Arabs, with one of the highest incidences in the world. OC is underdiagnosed, underreported, and mostly reported with breast cancer. This study aimed to conduct a systematic ... -
Genetic Epidemiology of Primary Congenital Glaucoma in the 22 Arab Countries: A Systematic Review.
( Taylor and Francis , 2021 , Article)Primary congenital glaucoma (PCG) is a rare glaucoma type that develops in early infantile period and contributes to an elevated pressure on ocular cavity. Variants in gene are the most encountered in PCG cases. The ... -
Genetic Epidemiology of Type 1 Diabetes in the 22 Arab Countries.
( Current Medicine Group , 2016 , Article)Type 1 diabetes (T1D) is a complex autoimmune disorder that results from the T cell-mediated destruction of the pancreatic β cells and is due to interactions between environmental and genetic factors. Although Arabs have ... -
Genetic epidemiology of Woodhouse-Sakati Syndrome in the Greater Middle East region and beyond: a systematic review
( BioMed Central Ltd , 2023 , Article Review)Background: Woodhouse-Sakati syndrome (WSS) is a rare, autosomal recessive genetic disorder with variable clinical manifestations mainly affecting the endocrine and nervous systems. The aim of this study was to systematically ... -
Genetic polymorphisms associated with obesity in the Arab world: a systematic review
( Springer Nature , 2021 , Article Review)Background: Obesity, one of the most common chronic health conditions worldwide, is a multifactorial disease caused by complex genetic and environmental interactions. Several association studies have revealed a considerable ... -
Genetic polymorphisms associated with type 2 diabetes in the Arab world: A systematic review and meta-analysis.
( Elsevier , 2019 , Article)T2DM reach epidemic levels in the Arab countries. In this study, we aimed to perform a systematic review and meta-analysis to underline the susceptibility genetic profile of Arab patients with T2DM that result from SNPs. ... -
Genetic polymorphisms of ICAM 1 and IL28 as predictors of liver fibrosis severity and viral clearance in hepatitis C genotype 4
( Elsevier , 2013 , Article)Background and objectivesIntercellular adhesion molecule-1 (ICAM-1) is located on chromosome 19p13.2, and this protein plays an important role in the pathogenesis of the hepatitis C virus (HCV). The rs12979860 polymorphism ...