Browsing College of Health Sciences by Title
Now showing items 678-697 of 1590
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Formulation, Cellular Uptake and Cytotoxicity of Thymoquinone-Loaded PLGA Nanoparticles in Malignant Melanoma Cancer Cells
( Dove Medical Press , 2020 , Article)Introduction: Thymoquinone (TQ) is the main active compound extracted from Nigella sativa a traditional herb with wide therapeutic applications and recognizable anticancer properties. This study aimed to formulate and ... -
Formulation, Characterization and Biological Activity Screening of Sodium Alginate-Gum Arabic Nanoparticles Loaded with Curcumin.
( MDPI , 2020 , Article)The approach of drug delivery systems emphasizes the use of nanoparticles as a vehicle, offering the optional property of delivering drugs as a single dose rather than in multiple doses. The current study aims to improve ... -
Frailty predicts adverse outcomes in older patients undergoing transcatheter aortic valve replacement (TAVR). From the National Inpatient Sample
( Elsevier , 2021 , Article)ObjectiveWe aimed to study the impact of frailty on the outcome of transcatheter aortic valve replacement (TAVR) procedures. MethodsThe National Inpatient Sample (NIS) database was queried for all patients aged ≥65 years ... -
Frequency of Clinically Important RH and Kell Blood Group Antigens Among Blood Donors in Qatar
( HBKU Press , 2016 , Conference Paper)Background Very limited information is available about the prevalence of blood groups among Qatari population and residents. The information about frequencies of different blood group antigens is important to manage, ... -
Frequency of Clinically Important RH and Kell Blood Group Antigens Among Blood Donors in Qatar
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Background Very limited information is available about the prevalence of blood groups among Qatari population and residents. The information about frequencies of different blood group antigens is important to manage, ... -
The frequency of polycystic ovary syndrome in young reproductive females in Qatar
( Dove Medical Press , 2016 , Article)This was a prospective cross-sectional study in which 126 female students between the ages of 18 and 30 years were evaluated for the frequency of polycystic ovary syndrome (PCOS) through clinical interview, questionnaire, ... -
Frizzled 4 regulates ventral blood vessel remodeling in the zebrafish retina
( Wiley , 2019 , Article)Familial exudative vitreoretinopathy (FEVR) is a rare congenital disorder characterized by a lack of blood vessel growth to the periphery of the retina with secondary fibrovascular proliferation at the vascular-avascular ... -
From text to e-text: perceptions of medical, dental and allied students about e-learning
( Elsevier , 2022 , Article)ObjectiveMore than a year ago, Pakistan like the rest of the word, was hit by a global pandemic, due to which students of higher education had to accept the new era and adapt to the electronic learning environment for the ... -
Fructose intake and its association with relative telomere length: an exploratory study among healthy Lebanese adults
( Frontiers Media , 2023 , Article)Introduction: Shorter relative telomere length (RTL) has been associated with increased incidence of morbidity. Although still disputed, available evidence suggests that dietary factors, including sugar-sweetened beverages ... -
Fruit and vegetable consumption and cardiovascular diseases among jordanians: A case-control study
( Czech National Institute of Public Health , 2020 , Article)Objectives: Fruit and vegetable intake has been reported as one of the significant protective factors against the development of cardiovascular diseases (CVD). This study aimed to assess the possible preventive effect of ... -
Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
( Wiley , 2020 , Article)© 2020 Wiley Periodicals, Inc. Myosin-binding protein C 3 (MYBPC3) variants are the most common cause of hypertrophic cardiomyopathy (HCM). HCM is a complex cardiac disorder due to its significant genetic and clinical ... -
Functional Characterization of Novel MC4R Variants Identified in Two Unrelated Patients with Morbid Obesity in Qatar
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)The leptin–melanocortin pathway is pivotal in appetite and energy homeostasis. Pathogenic variants in genes involved in this pathway lead to severe early-onset monogenic obesity (MO). The MC4R gene plays a central role in ... -
Funding sources and costs to deliver cardiac rehabilitation around the globe: Drivers and barriers.
( Elsevier , 2018 , Article)Cardiac rehabilitation (CR) reach is minimal globally, primarily due to financial factors. This study characterized CR funding sources, cost to patients to participate, cost to programs to serve patients, and the drivers ... -
Gene Expression Profiling and Protein Analysis Reveal Suppression of the C-Myc Oncogene and Inhibition JAK/STAT and PI3K/AKT/mTOR Signaling by Thymoquinone in Acute Myeloid Leukemia Cells
( MDPI , 2022 , Article)Overexpression of c-Myc plays an essential role in leukemogenesis and drug resistance, making c-Myc an attractive target for cancer therapy. However, targeting c-Myc directly is impossible, and c-Myc upstream regulator ... -
Gene Expression Profiling of Embryonic Human Neural Stem Cells and Dopaminergic Neurons from Adult Human Substantia Nigra
( Public Library of Science , 2011 , Article)Neural stem cells (NSC) with self-renewal and multipotent properties serve as an ideal cell source for transplantation to treat neurodegenerative insults such as Parkinson’s disease. We used Agilent’s and Illumina Whole ... -
Gene Expression Profiling of Embryonic Human Neural Stem Cells and Dopaminergic Neurons from Adult Human Substantia Nigra
( Hamad bin Khalifa University Press (HBKU Press) , 2012 , Conference Paper)Neural stem cells (NSC) with self-renewal and multipotent properties serve as an ideal cell source for transplantation to treat neurodegenerative insults such as Parkinson's disease. We used Agilent's and Illumina Whole ... -
General practitioner use of a C-reactive protein point-of-care test to help target antibiotic prescribing in patients with acute exacerbations of chronic obstructive pulmonary disease (the PACE study): study protocol for a randomised controlled trial.
( BioMed Central , 2017 , Article)Most patients presenting with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in primary care are prescribed an antibiotic, which may not always be appropriate and may cause harm. C-reactive protein ... -
The genetic basis and the diagnostic yield of genetic testing related to nonsyndromic hearing loss in Qatar
( Springer Nature , 2024 , Article)Hearing loss is the most predominant sensory defect occurring in pediatrics, of which, 66% cases are attributed to genetic factors. The prevalence of hereditary hearing loss increases in consanguineous populations, and the ... -
The Genetic Control of the Rheumatic Heart: Closing the Genotype-Phenotype Gap
( Frontiers Media , 2021 , Article Review)Rheumatic heart disease (RHD) is a heritable inflammatory condition characterized by carditis, arthritis, and systemic disease. Although remaining neglected, the last 3 years has seen some promising advances in RHD research. ... -
Genetic Diversity and Prevalence of in Qatar.
( Frontiers Media , 2021 , Article)is a common human intestinal parasite worldwide, and the causative agent of diarrhea, with the severity of disease ranging from asymptomatic to intense and debilitating infection. is known to consist of eight genetically ...