تصفح College of Health Sciences حسب الموضوع "Cancer"
السجلات المعروضة 1 -- 15 من 15
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Biological and biomedical functions of Penta-O-galloyl-D-glucose and its derivatives
( Springer Nature , 2014 , Other)Penta-O-galloyl-D-glucose (PGG) is a simple hydrolysable tannin in plants. PGG exists in two anomeric forms, α-PGG and β-PGG. While β-PGG can be found in a wide variety of plants, α-PGG is rather rare in nature. Numerous ... -
Correction to: Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance (Molecular Cancer, (2020), 19, 1, (57), 10.1186/s12943-020-01175-9)
( BMC , 2020 , Other)Following the publication of the original article [1], authors have noticed that one of the authors, Syed Shadab Raza, was missing in the Authors’ Contributions section. Please see below updated section. -
Development and In Vivo Testing of Smart Nanoparticles for Enhanced Anti-Cancer Activity and Reduced Cardiotoxicity Associated with Tyrosine Kinase Inhibitors
( Qatar University Press , 2021 , Poster)Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One TKI ... -
The Dual Specificity Role of Transcription Factor FOXO in Type 2-diabetes and Cancer
( Bentham Science Publishers , 2018 , Article Review)The FOXO (Forkhead box O) transcription factors are implicated in several signaling pathways and play a vital role in various cellular and physiological processes include for instance, ROS (reactive oxygen species) response, ... -
Editorial: Novel Targeted Therapy for Lung Cancer
( OMICS International , 2015 , Article)Lung cancer accounts for about 27% of all cancer deaths and considered as the leading cause of cancer-associated death worldwide. Genotype-driven therapeutics is a standard of care for majority of subgroup of NSCLC patients ... -
Evolution of Molecular Biology and Cancer: Crucial Turning Points and Startling Discoveries in a Continual Battle
( SciRes Literature , 2017 , Article)Cancer is the leading cause of morbidity and mortality worldwide. Comprehensive understanding of the evolution of molecular cell biology and cancer, and their crucial turning points in a chronological order, is of enormous ... -
Expression profile of MicroRNA: An Emerging Hallmark of Cancer.
( Bentham Science Publishers , 2019 , Article Review)MicroRNA (miRNAs), a class of small, endogenous non-coding RNA molecules of about 21-24 nucleotides in length, have unraveled a new modulatory network of RNAs that form an additional level of post-transcriptional gene ... -
Formulation and antioxidant properties of curcumin gum Arabic nanoparticles for delivery to cancer cells
( IOP Publishing , 2020 , Article)Curcumin nanoparticles (Cur/GANPs) were formulated based on gum arabic (GA) as a stabilizer coatings for nanoparticles through efficient synthesis approach. The current study investigated the antioxidant properties and ... -
Integrative ontology and pathway-based approach identifies distinct molecular signatures in transcriptomes of esophageal squamous cell carcinoma
( Elsevier , 2022 , Book chapter)Esophageal squamous cell carcinoma (ESCC) remains a serious concern globally due to many factors that including late diagnosis, lack of an ideal biomarker for diagnosis and prognosis, and high rate of mortality. In this ... -
microRNA 21 and long non-coding RNAs interplays underlie cancer pathophysiology: A narrative review
( Elsevier , 2024 , Article)Non-coding RNAs (ncRNAs) are a diverse group of functional RNA molecules that lack the ability to code for proteins. Despite missing this traditional role, ncRNAs have emerged as crucial regulators of various biological ... -
Novel Isosteviol Derivatives Induced Apoptosis In Human Lung Cancer
( Hamad bin Khalifa University Press (HBKU Press) , 2014 , Conference Paper)Background. Cancer metastasis is the major cause of cancer death. We previously reported novel isosteviols derivatives which induced cytotoxicity in lung cancer cells. The understanding of mechanisms which regulate lung ... -
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance.
( BMC , 2020 , Article Review)Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia ... -
Serum vitamin D concentrations are non-linearly related to breast cancer risk in postmenopausal women
( Qatar University Press , 2021 , Poster)Background: Post-menopausal women are at high risk for breast cancer. The association between serum 25-hydroxyvitamin D [25(OH)D] concentration and breast cancer in post-menopausal women is not well understood. Objectives: ... -
Substances Secreted by Starved Human Dermal Fibroblasts Enhancing the Wound Healing Process in Rat without Scar: A Potential Acellular System for Wound Healing
( Hamad Bin Khalifa University Press , 2016 , Conference Paper)Background Despite being a major cellular component of various engineered skin substituent, underlying mechanism of successful fibroblast transplantation in wound healing is not clear. Here we show that substances derived ... -
The spectrum of chromosomal translocations in the Arab world: ethnic-specific chromosomal translocations and their relevance to diseases
( Springer Science and Business Media Deutschland GmbH , 2022 , Article Review)Chromosomal translocations (CTs) are the most common type of structural chromosomal abnormalities in humans. CTs have been reported in several studies in the Arab world, but the frequency and spectrum of these translocations ...