Browsing College of Health Sciences by Subject "Factor H"

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Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59

Khaswaneh, Ramada R; Abu-El-Rub, Ejlal; Alzu'bi, Ayman; Almahasneh, Fatimah A; Almazari, Rawan A; Ai-Jariri, Heba F; Al-Zoubi, Raed M... more authors ... less authors ( Korean Tissue Engineering and Regenerative Medicine Society , 2025 , Article)
Background: Factor H and membrane inhibitor of reactive lysis (CD59) are key regulators of complement activation. Mesenchymal stem cells (MSCs) secrete Factor H and express CD59 to protect themselves from complement-mediated ...