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    Browsing College of Health Sciences by Subject "Pathogenesis"

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        Deletion of potD, encoding a putative spermidine-binding protein, results in a complex phenotype in Legionella pneumophila 

        Nasrallah, Gheyath K.; Abdelhady, Hany; Tompkins, Nicholas P.; Carson, Kaitlyn R.; Garduno, Rafael A. ( Elsevier GmbH , 2014 , Article)
        L. pneumophila is an intracellular pathogen that replicates in a membrane-bound compartment known as the Legionella-containing vacuole (LCV). We previously observed that the polyamine spermidine, produced by host cells or ...
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        Hepatitis E Viruses : Emerging and Transboundary Animal Viruses 

        Kumar, Harsh; Kamar, Nassim; Nasrallah, Gheyath K.; Kumar, Dinesh ( Springer , 2020 , Book chapter)
        Hepatitis E virus (HEV), member of genus Orthohepevirus in the family Hepeviridae, is the leading cause of hepatitis E. More than 20 million cases of hepatitis E virus (HEV) infection have been reported globally, out of ...
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        Markers associated with covid-19 susceptibility, resistance, and severity 

        Fakhroo, A.D.; Fakhroo, Aisha D.; Al Thani, Asmaa A.; Yassine, Hadi M. ( MDPI AG , 2021 , Article Review)
        In December 2019, the latest member of the coronavirus family, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in Wuhan, China, leading to the outbreak of an unusual viral pneumonia known as coronavirus ...
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        The molecular mechanism of nitric oxide in memory consolidation and its role in the pathogenesis of memory-related disorders 

        Bahdar, Zainab I.; Abu-El-Rub, Ejlal; Almazari, Rawan; Alzu’bi, Ayman; Al-Zoubi, Raed M. ( Springer Nature , 2025 , Article)
        Memory is a dynamic process of encoding, storing, and retrieving information. It includes sensory, short-term, and long-term memory, each with unique characteristics. Nitric oxide (NO) is a biological messenger synthesized ...
      • Pathogenic mechanisms, diagnostic, and therapeutic potential of microvesicles in diabetes and its complications 

        Alaa, Abbas; Almaghrbi, Heba; Giordo, Roberta; Zayed, Hatem; Pintus, Gianfranco ( Elsevier , 2024 , Article Review)
        Extracellular vesicles (EVs), particularly microvesicles (MVs), have gained significant attention for their role as mediators of intercellular communication in both physiological and pathological contexts, including diabetes ...
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        Recent Perspective About the Amyloid Cascade Hypothesis and Stem Cell-Based Therapy in the Treatment of Alzheimer's Disease 

        Marei, Hany E.; Althani, Asmaa; Suhonen, Jaana; El Zowalaty, Mohamed E.; Albanna, Mohammad A.; Cenciarelli, Carlo; Wang, Tengfei; Caceci, Thomas... more authors ... less authors ( Bentham Science , 2016 , Book chapter)
        Alzheimer's disease (AD) is a complex neurodegenerative condition that is clinically characterized by impaired cognitive functions. The major morphologically observed lesion of AD encompasses the accumulation of extracellular ...

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