Browsing College of Health Sciences by Subject "p300"

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Medicinal Phytocompounds as Potential Inhibitors of p300-HIF1? Interaction: A Structure-Based Screening and Molecular Dynamics Simulation Study

Suleman, Muhammad; Sayaf, Abrar Mohammad; Aftab, Sohail; Alissa, Mohammed; Alghamdi, Abdullah; Alghamdi, Suad A.; Alshehri, Mohammed A.; Yeoh, Kar Kheng; Crovella, Sergio; Shaito, Abdullah A.... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)
Background: Hypoxia plays a key role in cancer progression, mainly by stabilizing and activating hypoxia-inducible factor-1 (HIF-1). For HIF-1 to function under low oxygen conditions, it must interact with the transcriptional ...
Medicinal Phytocompounds as Potential Inhibitors of p300-HIF1α Interaction: A Structure-Based Screening and Molecular Dynamics Simulation Study

Suleman, Muhammad; Sayaf, Abrar Mohammad; Aftab, Sohail; Alissa, Mohammed; Alghamdi, Abdullah; Alghamdi, Suad A.; Alshehri, Mohammed A.; Yeoh, Kar Kheng; Crovella, Sergio; Shaito, Abdullah A.... more authors ... less authors ( MDPI , 2025 , Article)
Background: Hypoxia plays a key role in cancer progression, mainly by stabilizing and activating hypoxia-inducible factor-1 (HIF-1). For HIF-1 to function under low oxygen conditions, it must interact with the transcriptional ...