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Therapeutic potential of human olfactory bulb neural stem cells for spinal cord injury in rats.
(
Nature Publishing Group
, 2016 , Article)
STUDY DESIGN:
Adult human olfactory bulb neural stem cells (OBNSCs) were isolated from human patients undergoing craniotomy for tumor resection. They were genetically engineered to overexpresses green fluorescent protein ...
Adipose tissue dysfunction in cancer cachexia
(
Wiley Periodicals, Inc.
, 2018 , Article)
Cancer cachexia is a complex disorder that is driven by inflammation and metabolic imbalances, resulting in extreme weight loss. Adipose tissue, a main player in cancer cachexia, is an essential metabolic and secretory ...
Specific bioactive compounds in ginger and apple alleviate hyperglycemia in mice with high fat diet-induced obesity via Nrf2 mediated pathway
(
Elsevier
, 2017 , Article)
Prolonged hyperglycemia activates the formation of advanced glycation end-products (AGEs). Major
dicarbonyl compounds such as methylglyoxal or glyoxal are found to be the main precursors of AGEs
and N(e)-(carboxymethyl)lysine ...
A potential link between oxidative stress and endothelial-to-mesenchymal transition in systemic sclerosis
(
Frontiers Media S.A.
, 2018 , Article Review)
Systemic sclerosis (SSc), an autoimmune disease that is associated with a number of genetic and environmental risk factors, is characterized by progressive fibrosis and microvasculature damage in the skin, lungs, heart, ...
Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells
(
Taylor and Francis Ltd
, 2016 , Article)
Novel 1,5-diphenyl-6-substituted-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones were synthesized and characterized. All compounds were screened for their anti-proliferative activities in five different cancer cell lines. The results ...
Seroprevalence of hepatitis E virus among blood donors in Qatar (2013-2016)
(
Wiley
, 2017 , Article)
BACKGROUND
Hepatitis E virus (HEV) is an RNA virus transmitted mainly through zoonotic transmission or fecal–oral route. More than 80% of Qatar's population are expatriates, including many coming from hyperendemic ...
Implementing 360 Quantified Self for childhood obesity: Feasibility study and experiences from a weight loss camp in Qatar
(
BioMed Central Ltd.
, 2017 , Article)
Background: The explosion of consumer electronics and social media are facilitating the rise of the Quantified Self (QS) movement where millions of users are tracking various aspects of their daily life using social media, ...
Arrhythmogenic calmodulin E105A mutation alters cardiac RyR2 regulation leading to cardiac dysfunction in zebrafish
(
Wiley
, 2019 , Article)
Calmodulin (CaM) is a universal calcium (Ca )-binding messenger that regulates many vital cellular events. In cardiac muscle, CaM associates with ryanodine receptor 2 (RyR2) and regulates excitation-contraction coupling. ...
Chinese Famine and the diabetes mellitus epidemic.
(
Nature Research
, 2019 , Article)
We thank Li et al. (The effect of the Chinese Famine on type 2 diabetes mellitus epidemics. Nat. Rev. Endocrinol. 15, 313–314 (2019))1 for their interest in our paper and agree that some studies on the association between ...
Early life exposure to 1959-1961 Chinese famine exacerbates association between diabetes and cardiovascular disease.
(
Wiley
, 2019 , Article)
We aimed to assess whether early life exposure to the Chinese famine (1959-1961) modifies the association between type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) in adulthood. Data from 4247 adults born ...