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Enhanced Identification of Transcriptional Enhancers Provides Mechanistic Insights into Diseases.
(
Cell Press
, 2016 , Article)
Enhancers are distal cis-regulatory DNA elements that increase the expression of target genes. Various experimental and computational approaches including chromatin signature profiling have been developed to predict enhancers ...
Accredited genetic testing in the Arab Gulf region: reinventing the wheel.
(
Nature Publishing Group
, 2016 , Article)
Accredited genetic testing in the Arab Gulf region: reinventing the wheel.
Alcohol Consumption, Early-Onset Drinking, and Health-Related Consequences in Adolescents Presenting at Emergency Departments in England
(
Elsevier
, 2017 , Article)
PurposeGlobally, alcohol use is the leading cause of ill health and life years lost in adolescents, although its clinical impact is often overlooked, particularly in England where most research is based in schools. This ...
In vitro and in vivo inhibition of aldose reductase and advanced glycation end products by phloretin, epigallocatechin 3-gallate and [6]-gingerol
(
Elsevier
, 2016 , Article)
Abstract Hyperglycemic stress activates polyol pathway and aldose reductase (AR) key enzyme responsible for generating secondary complications during diabetes. In this study the therapeutic potential of phloretin, ...
Recent Perspective About the Amyloid Cascade Hypothesis and Stem Cell-Based Therapy in the Treatment of Alzheimer's Disease
(
Bentham Science
, 2016 , Book chapter)
Alzheimer's disease (AD) is a complex neurodegenerative condition that is
clinically characterized by impaired cognitive functions. The major morphologically
observed lesion of AD encompasses the accumulation of extracellular ...
Association between mass media and body weight concern among Jordanian adolescents’ residents of Amman: the role of gender and obesity.
(
Springer Verlag (Germany)
, 2016 , Article)
Objectives
Body image in the mass media promotes an unrealistic picture of body shape that leads to body dissatisfaction among adolescentsQuery. Therefore, the study presented in this paper aimed to assess the association ...
Communication Among Parents Who Share Physical Custody After Divorce or Separation
(
SAGE Publications
, 2015 , Article)
This study produces a grounded theory of the process of communication
with former partners for 30 men and women who share physical and legal
custody of their children following divorce or separation. The formality of ...
Therapeutic potential of human olfactory bulb neural stem cells for spinal cord injury in rats.
(
Nature Publishing Group
, 2016 , Article)
STUDY DESIGN:
Adult human olfactory bulb neural stem cells (OBNSCs) were isolated from human patients undergoing craniotomy for tumor resection. They were genetically engineered to overexpresses green fluorescent protein ...
Physico-chemical characterization of biochars from solid municipal waste for use in soil amendment
(
Elsevier B.V.
, 2016 , Article)
The fast economic and demographic growth lead to generation of large amounts of solid wastes placing Qatar on top of most nations with a per capita solid waste generation of nearly 2.5 milliontons/year of which 60% is ...
Tea flavanols block advanced glycation of lens crystallins induced by dehydroascorbic acid
(
American Chemical Society
, 2015 , Article)
Growing evidence has shown that ascorbic acid (ASA) can contribute to protein glycation and the formation of
advanced glycation end products (AGEs), especially in the lens. The mechanism by which ascorbic acid can cause ...