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Sanguinarine Induces Apoptosis in Papillary Thyroid Cancer Cells via Generation of Reactive Oxygen Species.
(
MDPI
, 2020 , Article)
Sanguinarine (SNG), a natural compound with an array of pharmacological activities, has promising therapeutic potential against a number of pathological conditions, including malignancies. In the present study, we have ...
Systematic Review of the Respiratory Syncytial Virus (RSV) Prevalence, Genotype Distribution, and Seasonality in Children from the Middle East and North Africa (MENA) Region
(
MDPI
, 2020 , Article)
Respiratory syncytial virus (RSV) is one of the most common viruses to infect children worldwide and is the leading cause of lower respiratory tract illness (LRI) in infants. This study aimed to conduct a systematic review ...
Dasatinib and PD-L1 inhibitors provoke toxicity and inhibit angiogenesis in the embryo
(
Elsevier
, 2021 , Article)
Dasatinib is a targeted cancer therapy, while programmed death ligand 1 (PD-L1) inhibitors are a form of immune checkpoint therapy used to treat various types of cancers. Several studies showed the potential efficacy of ...
Screening and brief interventions for adolescent alcohol use disorders presenting through emergency departments: a research programme including two RCTs
(
NIHR Journals Library
, 2020 , Article)
BACKGROUND:
Alcohol consumption and related harm increase steeply from the ages of 12–20 years. Adolescents in the UK are among the heaviest drinkers in Europe. Excessive drinking in adolescents is associated with ...
Organ-specific toxicity evaluation of stearamidopropyl dimethylamine (SAPDMA) surfactant using zebrafish embryos
(
Elsevier
, 2020 , Article)
Surfactants are widely used in the industry of detergents, household products, and cosmetics. SAPDMA is a cationic surfactant that is used mostly in cosmetics, conditioning agents and has recently gained attention as a ...
Co‑prevalence of human Papillomaviruses (HPV) and Epstein–Barr virus (EBV) in healthy blood donors from diverse nationalities in Qatar
(
BMC
, 2020 , Article)
Background: Infections by both human oncoviruses, human Papillomaviruses (HPV) and Epstein–Barr virus (EBV) are
very common in the adult human population and are associated with various malignancies. While HPV is ...
Women-Only Cardiac Rehabilitation Delivery Around the World
(
Elsevier
, 2020 , Article & Conference Proceedings)
Background: Women utilize cardiac rehabilitation (CR) significantly less than men. Gender-tailored CR improves adherence and mental
health outcomes when compared to traditional programs. This study ascertained the ...
Willingness to participate in genome testing: a survey of public attitudes from Qatar
(
Springer
, 2020 , Article)
Genomics has the potential to revolutionize medical approaches to disease prevention, diagnosis, and treatment, but it does not come without challenges. The success of a national population-based genome program, like the ...
Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
(
Elsevier
, 2021 , Article)
The aim of this study was to prepare, characterize, and determine the in vitro anticancer effects of platinum-doped magnesia (Pt/MgO) nanoparticles. The chemical compositions, functional groups, and size of nanoparticles ...
Aberrant DNA methylation of PTPRG as one possible mechanism of its under-expression in CML patients in the State of Qatar
(
Wiley Open Access
, 2020 , Article)
Several studies showed that aberrant DNA methylation is involved in leukemia and cancer pathogenesis. Protein tyrosine phosphatase receptor gamma (PTPRG) expression is a natural inhibitory mechanism that is downregulated ...