Search
Now showing items 151-160 of 669
The role of genetic and epigenetic GNAS alterations in the development of early-onset obesity
(
Elsevier
, 2023 , Article)
BackgroundGNAS (guanine nucleotide-binding protein, alpha stimulating) is an imprinted gene that encodes Gsα, the α subunit of the heterotrimeric stimulatory G protein. This subunit mediates the signalling of a diverse ...
Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar
(
BMJ Publishing Group
, 2023 , Article)
Objective To assess the evolution of COVID-19 severity and fatality in a unique setting that consistently applied, throughout the pandemic, rigorous and standardised criteria for defining severe COVID-19 outcomes.
Methods ...
In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model
(
Elsevier
, 2024 , Article)
Heart failure (HF) is a multifactorial, heterogeneous systemic disease that is considered one of the leading causes of death and morbidity worldwide. It is well-known that endothelial dysfunction (ED) plays an important ...
Immunomodulatory and anti-inflammatory effects of sesamin: mechanisms of action and future directions.
(
Taylor and Francis
, 2021 , Article)
Inflammation is associated with the development and progression of various disorders including atherosclerosis, diabetes mellitus and cancer. Sesamin, a fat-soluble lignan derived from seeds and oil, has received increased ...
White Button Mushroom, Agaricus bisporus (Agaricomycetes), and a Probiotics Mixture Supplementation Correct Dyslipidemia without Influencing the Colon Microbiome Profile in Hypercholesterolemic Rats.
(
Int J Med Mushrooms
, 2020 , Article)
Consumption of foods rich in dietary fiber has attracted considerable attention for lowering blood cholesterol and triglycerides through attenuation of gut microbiome. Diets rich in fiber may provide substrates for microbes ...
Implementation and evaluation of a preceptor educational development programme involving the health cluster colleges at Qatar University
(
Wiley
, 2022 , Article)
Background: ‘The Practice Educators' Academy Programme’ is an innovative educational intervention developed following a preceptor-focussed needs assessment. The primary aim of this study was to evaluate the programme's ...
U-shaped association between dietary calcium density intake during adolescence and hypertension in adulthood-a 20-y longitudinal nationwide study in China
(
Cambridge University Press
, 2021 , Article)
Background and Aims: We assessed longitudinal association between calcium intake during adolescence and hypertension in adulthood. Methods and Results: Longitudinal study data of 1611 participants from the China Health and ...
Topical treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials
(
Elsevier
, 2023 , Article)
BackgroundAtopic dermatitis (AD) is a common skin condition with multiple topical treatment options, but uncertain comparative effects. ObjectiveWe sought to systematically synthesize the benefits and harms of AD prescription ...
"It's disappointing and it's pretty frustrating, because it feels like it's something that will never go away." A qualitative study exploring individuals' beliefs and experiences of Achilles tendinopathy.
(
Public Library of Science
, 2020 , Article)
Achilles tendinopathy (AT) is a common and often persistent musculoskeletal disorder affecting both athletic and non-athletic populations. Despite the relatively high incidence there is little insight into the impact and ...
Pesticide residues in foods and water in Qatar and their impact on food exposure risk assessment
(
Emerald
, 2021 , Article)
Purpose: The purposes of this study were to analyze fruits, vegetables, water and soil for organochlorine pesticide (OCP) residues and to assess the food exposure of these pesticides in Qatar. Design/methodology/approach: ...