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Prior Statins Use and Risk of Mortality and Severe Disease from COVID-19: A Systematic Review and Meta-Analysis
(
Oxford University Press
, 2021 , Article)
Background
Statins up-regulate angiotensin converting enzyme-2, the receptor of SARS-CoV-2, while also exhibiting pleiotropic antiviral, antithrombotic and anti-inflammatory properties. Uncertainties exist about their ...
Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2.
(
Frontiers Media
, 2021 , Article)
The number of confirmed COVID-19 cases is rapidly increasing with no direct treatment for the disease. Few repurposed drugs, such as Remdesivir, Chloroquine, Hydroxychloroquine, Lopinavir, and Ritonavir, are being tested ...
Thrombotic and Hypercoagulability Complications of COVID-19: An Update
(
Dovepress
, 2021 , Article)
The current COVID-19 pandemic emerged in December 2019, in China, affecting millions of people worldwide. COVID-19 is mainly a disease of the respiratory system, yet systematic complications have also been reported among ...
Equity in vaccine trials for higher weight people ? Protocol for a rapid review of inclusion and exclusion criteria for higher weight people in clinical trials for COVID-19
(
BMJ Publishing Group
, 2021 , Article)
Introduction Vaccination is a public health strategy that aims to reduce the burden of viral illness, especially
important for populations known or likely to be at increased risk for inequitable outcomes due to the ...
Nutrition Management in COVID-19 Quarantine: Hospital-Based Study
(
Cambridge University Press
, 2021 , Article)
Background:
This hospital-based study aimed to evaluate the nutritional status and dietary habits for COVID-19 patients, the amount of nutrients provided to the patients in the hospital and to detect the predictors of ...
Mental distress and its associations with behavioral outcomes during the COVID-19 pandemic: a national survey of Chinese adults
(
Elsevier
, 2021 , Article)
ObjectivesThis study aimed to evaluate associations between mental distress and COVID-19-related changes in behavioral outcomes and potential modifiers (age, gender, educational attainment) of such associations. Study ...
SARS-CoV-2 infection among primary healthcare workers: a cross- sectional study
(
GERMS
, 2021 , Article)
Healthcare workers (HCWs) are critical to the healthcare system and are at an increased risk of SARS-CoV-2 infection. They may acquire infections from the community and their work settings. To date, the majority of the ...
BNT162b2 and mRNA-1273 COVID-19 vaccine effectiveness against the SARS-CoV-2 Delta variant in Qatar.
(
Nature Researc
, 2021 , Article)
With the global expansion of the highly transmissible SARS-CoV-2 Delta (B.1.617.2) variant, we conducted a matched test-negative case-control study to assess the real-world effectiveness of COVID-19 messenger RNA vaccines ...
Nasopharyngeal Expression of Angiotensin-Converting Enzyme 2 and Transmembrane Serine Protease 2 in Children within SARS-CoV-2-Infected Family Clusters.
(
American Society for Microbiology
, 2021 , Article)
Lower levels of angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) in the nasal epithelium of children may be related to a lower incidence of severe acute respiratory syndrome coronavirus ...