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Dietary patterns associated with the risk of osteoporosis in postmenopausal women
(
BMC
, 2023 , Article)
The purpose of this study is to investigate the association between dietary patterns and the risk associated with osteoporosis in Jordanian postmenopausal women recently diagnosed with osteoporosis. A case–control study ...
Use of Animal Models for Investigating Cardioprotective Roles of SGLT2 Inhibitors
(
Springer
, 2023 , Article Review)
Sodium-glucose co-transporter 2 (SGLT2) inhibitors represent one type of new-generation type 2 diabetes (T2DM) drug treatment. The mechanism of action of an SGLT2 inhibitor (SGLT2i) in treating T2DM depends on lowering ...
Chapter Four Controlling cell proliferation by targeting cyclin-dependent kinase 6 using drug repurposing approach
(
Elsevier
, 2023 , Book chapter)
Cyclin-dependent kinase 6 (CDK6) is an essential kinase in cell cycle progression, which is a viable target for inhibitors in various malignancies, including breast cancer. This study aimed to virtually screen efficient ...
Molecular characterization of circadian gene expression and its correlation with survival percentage in colorectal cancer patients
(
Elsevier
, 2023 , Book chapter)
Colorectal cancer (CRC) is a form of cancer characterized by many symptoms and readily metastasizes to different organs in the body. Circadian rhythm is one of the many processes that is observed to be dysregulated in ...
Changes in alcohol-related perceptions and behaviour among Vietnamese early career doctors after graduation
(
IOS Press
, 2023 , Article)
BACKGROUND: Vietnamese medical students believe becoming "strong" drinkers is important for their future career working as doctor. However, it is unclear if this is a temporary behaviour associated with life as a student, ...
Diminishing benefits of urban living for children and adolescents’ growth and development
(
Springer Nature
, 2023 , Article)
Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million ...
A comparison study of prevalence, awareness, treatment and control rates of hypertension and associated factors among adults in China and the United States based on national survey data
(
KeAi Communications Co.
, 2023 , Article)
ObjectiveThis study compared the prevalence, awareness, treatment and control of hypertension and associated factors in China and the United States (US). MethodsAdult data from nationally representative samples were derived ...
Identification of dysregulated canonical pathways associated with pathogenesis and progression of Amyotrophic Lateral Sclerosis—An integrated bioinformatics approach
(
Elsevier
, 2023 , Article)
The mechanisms responsible for the pathogenesis and progression of Amyotrophic Lateral Sclerosis (ALS) remain poorly understood, making the diagnosis of ALS challenging. We aimed to find the novel gene biomarkers via ...
Non-coding RNAs as biomarkers of myocardial infarction
(
Elsevier
, 2023 , Article)
Non-coding RNAs (ncRNAs) encompass a family of ubiquitous RNA molecules that lack protein-coding potential and have tissue-specific expression. A significant body of evidence indicates that ncRNA's aberrant expression plays ...
Genomic Alterations, Gene Expression Profiles and Functional Enrichment of Normal-Karyotype Acute Myeloid Leukaemia Based on Targeted Next-Generation Sequencing
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Characterising genomic variants is paramount in understanding the pathogenesis and heterogeneity of normal-karyotype acute myeloid leukaemia (AML-NK). In this study, clinically significant genomic biomarkers were ascertained ...