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A profound computational study to prioritize the disease-causing mutations in PRPS1 gene.
(
Springer Verlag
, 2017 , Article)
Charcot-Marie-Tooth disease (CMT) is one of the most commonly inherited congenital neurological disorders, affecting approximately 1 in 2500 in the US. About 80 genes were found to be in association with CMT. The phosphoribosyl ...
CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion.
(2017 , Article)
We have previously validated three novel CD44-downstream positively regulated transcriptional targets, including Cortactin, Survivin and TGF-β2, and further characterized the players underlying their separate signaling ...
Dietary patterns and the risk of coronary heart disease among Jordanians: A caseecontrol study
(
Elsevier
, 2017 , Article)
Background and Aims
Dietary pattern and lifestyle have been reported to be significant risk factors in the development of coronary heart diseases (CHD). The contribution degree of these dietary risk factors in CHD ...
Burden, screening, and treatment of depressive and anxious symptoms among women referred to cardiac rehabilitation: a prospective study
(
BioMed Central
, 2017 , Article)
Background
Cardiovascular disease (CVD) is one of the leading causes of morbidity and mortality among women. Women with CVD experience a greater burden of psychosocial distress than men, and practice guidelines promote ...
Levels of physical activity and sleep patterns among older people with dementia living in long-term care facilities: A 24-hour snapshot
(
Elsevier
, 2017 , Article)
Objectives
To objectively measure over a 24-hour period the daytime and nighttime levels of physical activity and sleep patterns of older people with dementia living in long-term care facilities.
Study design
Nested ...
Hospital effect on infections after four major surgeries: Outlier and volume-outcome analysis using all-inclusive state data
(
Elsevier
, 2017 , Article)
Hospital volume is known to have a direct impact on outcomes of major surgeries. However, it is unclear if the evidence applies specifically to surgical site infections. To determine if there are procedure-specific hospital ...
Two patients with Canavan disease and structural modeling of a novel mutation.
(
Springer US
, 2017 , Article)
Canavan disease (CD) is a rare fatal childhood neurological autosomal recessive genetic disease caused by mutations in the ASPA gene, which lead to catalytic deficiency of the ASPA enzyme, which catalyzes the hydrolysis ...
Salt intake, blood pressure, and socioeconomic disparities among government employees in Sri Lanka: a cross-sectional study
(
Qatar University
, 2017 , Article)
Our study estimated salt intake, examined the association between blood pressure (BP) and salt intake, and explored the socioeconomic variations in salt intake among administrators (government employees). This is a ...
Fast Foods Perception Among Adolescents by Gender and Weight Status
(
Sage
, 2017 , Article)
Background: Fast food restaurants have become widespread in both developed and developing countries due to nutritional and economic transitions. The frequency of fast food intake is relatively high among adolescents; ...
Alcohol Consumption, Early-Onset Drinking, and Health-Related Consequences in Adolescents Presenting at Emergency Departments in England
(
Elsevier
, 2017 , Article)
PurposeGlobally, alcohol use is the leading cause of ill health and life years lost in adolescents, although its clinical impact is often overlooked, particularly in England where most research is based in schools. This ...