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Using a therapeutic companion robot for dementia symptoms in long-term care: reflections from a cluster-RCT.
(
Taylor & Francis (Routledge)
, 2017 , Article)
We undertook a cluster-randomised controlled trial exploring the effect of a therapeutic companion robot (PARO) compared to a look-alike plush toy and usual care on dementia symptoms of long-term care residents. Complementing ...
Evaluation of Global Genomic DNA Methylation in Human Whole Blood by Capillary Electrophoresis UV Detection
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Hindawi Publishing Corporation
, 2017 , Article)
Alterations in global DNA methylation are implicated in various pathophysiological processes. The development of simple and quick, yet robust, methods to assess DNA methylation is required to facilitate its measurement and ...
Meta-analysis in evidence-based healthcare: a paradigm shift away from random effects is overdue.
(
University of Adelaide, Joanna Briggs Institute
, 2017 , Article)
Each year up to 20 000 systematic reviews and meta-analyses are published whose results influence healthcare decisions, thus making the robustness and reliability of meta-analytic methods one of the world's top clinical ...
Novel Quinuclidinone Derivatives Induced Apoptosis in Human Breast Cancer via Targeting P53
(
Elsevier
, 2017 , Article)
Small molecules that can target human cancers have been highly sought to increase the anticancer efficacy, the present work describes the design and synthesis of novel series of five quinuclidinone derivatives (2a-2e). ...
Prevalence and molecular profiling of Epstein Barr virus (EBV) among healthy blood donors from different nationalities in Qatar.
(
Public Library of Science
, 2017 , Article)
The Epstein-Barr virus (EBV) is the causative agent of infectious mononucleosis. EBV is highly prevalent lymphotropic herpesvirus and has been linked to several malignancies. Transmission is generally by oral secretions, ...
Estimating Seroprevalence of Herpes Simplex Virus Type 1 among Different Middle East and North African Male Populations Residing in Qatar
(
Wiley
, 2017 , Article)
HSV-1 epidemiology in the Middle East and North Africa (MENA) remains poorly understood. Our study aimed to measure HSV-1 antibody prevalence (seroprevalence) and its age-distribution among select MENA populations residing ...
Genotype-phenotype correlation in patients with isovaleric acidaemia: comparative structural modelling and computational analysis of novel variants.
(
Oxford University Press (OUP)
, 2017 , Article)
Isovaleric acidaemia (IVA) is an autosomal recessive inborn error of leucine metabolism. It is caused by a deficiency in the mitochondrial isovaleryl-CoA dehydrogenase (IVD) enzyme. In this study, we investigated eight ...
Cysteamine revisited: repair of arginine to cysteine mutations.
(
Springer Verlag
, 2017 , Article)
Cysteamine is a small aminothiol endogenously derived from coenzyme A degradation. For some decades, synthetic cysteamine has been employed for the treatment of cystinosis, and new uses of the drug continue to emerge. In ...
Stage of change toward “9-a-day” not “5-a-day” is associated with lower body weight
(
Emerald Publishing
, 2017 , Article)
Purpose- This study aimed to assess the students’ stage of change (SOC) for fruits and
vegetables (FV) consumption using the 5-a-day and 9-a-day patterns; to validate a tool to
measure SOC for consuming 5-a-day and 9-a-day ...
Geographical outcome disparities in infection occurrence after colorectal surgery: An analysis of 58,096 colorectal surgical procedures
(
Elsevier Ltd
, 2017 , Article)
Background Despite improved surgical practices and in-hospital surveillance systems, surgical site infections remain a major public health problem worldwide and often require readmission to hospital. The aim was to apply ...