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Now showing items 11-20 of 28
Zebrafish larvae as a model to demonstrate secondary iron overload.
(
Wiley
, 2018 , Article)
Thalassemia is the most common genetically inherited blood disorder arising from a defect in hemoglobin production, resulting in ineffective erythropoiesis and severe hemolytic anemia. While transfusion therapy corrects ...
Detection and Phylogenetic Analysis of Human Pegivirus (GBV-C) Among Blood Donors and Patients Infected With Hepatitis B Virus (HBV) in Qatar
(
Wiley
, 2015 , Article)
Human Pegivirus (HPgV), formerly GB virus-C/
Hepatitis G virus (GBV-C/HGV), collectively
known as GBV-C, is widely spread and has
been reported to be associated with non-A–E
hepatitis. To our knowledge, no previous ...
Human microbiome and its association with health and diseases
(
Wiley
, 2016 , Article)
Human microbiota are distinct communities of microorganisms that resides at different body
niches. Exploration of the human microbiome has become a reality due to the availability of
powerful metagenomics and metatranscriptomic ...
Detection and Genotyping of Torque Teno Virus (TTV) in Healthy Blood Donors and Patients Infected With HBV or HCV in Qatar
(
Wiley Periodicals, Inc
, 2015 , Article)
Torque Teno virus (TTV) has been associated
with non A–G hepatitis. The goal of this study
was to estimate the infection rates and genotypic
characteristics of TTV in the State of Qatar.
A total of 644 blood samples ...
A YEAST TWO-HYBRID SCREEN REVEALS A STRONG INTERACTION BETWEEN THE LEGIONELLA CHAPERONIN Hsp60 AND THE HOST CELL SMALL HEAT SHOCK PROTEIN Hsp10
(
Akadémiai Kiadó
, 2015 , Article)
L. pneumophila is an intracellular bacterium that replicates inside a membrane-
bound vacuole called Legionella-containing vacuole (LCV), where it plentifully
liberates its HtpB chaperonin. From LCV, HtpB reaches the ...
Deletion of potD, encoding a putative spermidine-binding protein, results in a complex phenotype in Legionella pneumophila
(
Elsevier GmbH
, 2014 , Article)
L. pneumophila is an intracellular pathogen that replicates in a membrane-bound compartment known as the Legionella-containing vacuole (LCV). We previously observed that the polyamine spermidine, produced by host cells or ...
Using Zebrafish for Investigating the Molecular Mechanisms of Drug-Induced Cardiotoxicity
(
Hindawi Publishing Corporation
, 2018 , Article)
Over the last decade, the zebrafish (Danio rerio) has emerged as amodel organismfor cardiovascular research.Zebrafish have several advantages over mammalian models. For instance, the experimental cost of using zebrafish ...
Seroprevalence and incidence of hepatitis E virus among blood donors: A review.
(
Wiley
, 2017 , Article)
Hepatitis E virus (HEV) is an RNA virus with 4 main genotypes. HEV-1 and HEV-2 infect solely humans, while HEV-3 and HEV-4 infect humans and various animals such as pigs, deer, and rabbits. HEV-5 and HEV-6 infect mainly ...
The Role of Cardiac Myosin Binding Protein C3 in Hypertrophic Cardiomyopathy- Progress and Novel Therapeutic Opportunities
(
Wiley
, 2016 , Article)
Hypertrophic cardiomyopathy (HCM) is a common autosomal dominant genetic cardiovascular disorder marked by genetic and phenotypic heterogeneity. Mutations in the gene encodes the cardiac myosin-binding protein C, cMYBPC3 ...
A systematic investigation of the bio-toxicity of core-shell magnetic mesoporous silica microspheres using zebrafish model
(
Elsevier
, 2018 , Article)
Abstract In this work, shearing interface coassembly in biliquid phase systems is employed to synthesize biocompatible core-shell magnetic mesoporous silica microspheres with uniform size of about 600 nm, perpendicular ...