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Diagnostic Efficiency of Three Fully Automated Serology Assays and Their Correlation with a Novel Surrogate Virus Neutralization Test in Symptomatic and Asymptomatic SARS-COV-2 Individuals
(
MDPI
, 2020 , Article)
Abstract: To support the deployment of serology assays for population screening during the
COVID-19 pandemic, we compared the performance of three fully automated SARS-CoV-2 IgG assays: Mindray CL-900i® (target: spike [S] ...
The prevalence of HEV among non-A-C hepatitis in Qatar and efciency of serological markers for the diagnosis of hepatitis E
(
BMC
, 2021 , Article)
Background: The rapid growth of Qatar in the last two decades has attracted a large influx of immigrant workers
who mostly come from HEV-hyperendemic countries. Thus, we aim to investigate the prevalence of HEV among acute ...
Short- and longer-term all-cause mortality among SARS-CoV-2- infected individuals and the pull-forward phenomenon in Qatar: a national cohort study
(
Elsevier
, 2023 , Article)
ObjectivesWe assessed short-, medium-, and long-term all-cause mortality risks after a primary SARS-CoV-2 infection. MethodsA national, matched, retrospective cohort study was conducted in Qatar to assess risk of all-cause ...
SARS-CoV-2 infection and effects of age, sex, comorbidity, and vaccination among older individuals: A national cohort study
(
Wiley
, 2023 , Article)
Background: We investigated the contribution of age, coexisting medical conditions, sex, and vaccination to incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and of severe, critical, or ...
Exploring the natural products chemical space to abrogate the F3L-dsRNA interface of monkeypox virus to enhance the immune responses using molecular screening and free energy calculations
(
Frontiers Media SA
, 2023 , Article)
Amid the ongoing monkeypox outbreak, there is an urgent need for the rapid development of effective therapeutic interventions capable of countering the immune evasion mechanisms employed by the monkeypox virus (MPXV). The ...
Seroprevalence of hepatitis E virus (HEV) among male craft and manual workers in Qatar (2020–2021)
(
Elsevier
, 2023 , Article)
BackgroundThe rapid growth of Qatar in the last two decades has attracted a large influx of immigrant craft and manual workers (CMWs) seeking employment in jobs associated with food handling, domestic service, and construction. ...
History of primary-series and booster vaccination and protection against Omicron reinfection
(
American Association for the Advancement of Science
, 2023 , Article)
Laboratory evidence suggests a possibility of immune imprinting for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We investigated the differences in the incidence of SARS-CoV-2 reinfection in a ...
Addressing bias in the definition of SARS-CoV-2 reinfection: implications for underestimation
(
Frontiers Media
, 2024 , Article)
Introduction: Reinfections are increasingly becoming a feature in the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, accurately defining reinfection poses methodological ...
Effectiveness of two and three doses of COVID-19 mRNA vaccines against infection, symptoms, and severity in the pre-omicron era: A time-dependent gradient
(
Elsevier
, 2024 , Article)
BackgroundVaccines were developed and deployed to combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study aimed to characterize patterns in the protection provided by the BNT162b2 and ...
SARS-CoV-2 infection triggers more potent antibody-dependent cellular cytotoxicity (ADCC) responses than mRNA-, vector-, and inactivated virus-based COVID-19 vaccines
(
Wiley
, 2024 , Article)
Neutralizing antibodies (NAbs) are elicited after infection and vaccination and have been well studied. However, their antibody-dependent cellular cytotoxicity (ADCC) functionality is still poorly characterized. Here, we ...