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Expression profile of MicroRNA: An Emerging Hallmark of Cancer.
(
Bentham Science Publishers
, 2019 , Article Review)
MicroRNA (miRNAs), a class of small, endogenous non-coding RNA molecules of about 21-24 nucleotides in length, have unraveled a new modulatory network of RNAs that form an additional level of post-transcriptional gene ...
RNA splicing: a dual-edged sword for hepatocellular carcinoma
(
Springer
, 2022 , Article Review)
RNA splicing is the fundamental process that brings diversity at the transcriptome and proteome levels. The spliceosome complex regulates minor and major processes of RNA splicing. Aberrant regulation is often associated ...
Relationship between body mass index, risk of venous thromboembolism and pulmonary embolism: A systematic review and dose-response meta-analysis of cohort studies among four million participants
(
Elsevier
, 2020 , Article Review)
Background: The relationship between body mass index (BMI) and risk of venous thromboembolism (VTE) and pulmonary embolism (PE) is a controversial issue. This dose-response meta-analysis was performed to investigate the ...
The impact of health status, diet and lifestyle on non-alcoholic fatty liver disease: Narrative review
(
Wiley
, 2022 , Article Review)
Non-alcoholic fatty liver disease (NAFLD) is defined as the abnormal accumulation of triglycerides in the liver. NAFLD has a global prevalence of almost 30%, while incidence is rising with increasing levels of obesity, ...
The Interplay Between Diet and the Epigenome in the Pathogenesis of Type-1 Diabetes
(
Frontiers
, 2021 , Article Review)
The autoimmune disease, Type 1 Diabetes Mellitus (T1DM), results in the destruction of pancreatic β-cells, and the International Diabetes Federation reports that its incidence is increasing worldwide. T1DM is a complex ...
Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications
(
MDPI
, 2020 , Article Review)
Vitamin D and its active metabolites are important nutrients for human skeletal health. UV irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the liver and kidneys into its active form, ...
Severe acute respiratory syndrome coronavirus-2 natural animal reservoirs and experimental models: systematic review.
(
John Wiley and Sons
, 2020 , Article Review)
The current severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) outbreak has been rapidly spreading worldwide, causing serious global concern. The role that animal hosts play in disease transmission is still ...
Better reporting standards are needed to enhance the quality of hop testing in the setting of ACL return to sport decisions: a narrative review.
(
BMJ Publishing Group
, 2020 , Article Review)
There is a lack of consistency in return to sport (RTS) assessments, in particular hop tests to predict who will sustain a reinjury following anterior cruciate ligament (ACL) reconstruction. Inconsistent test battery content ...
Disturbed hemodynamics and oxidative stress interaction in endothelial dysfunction and AAA progression: Focus on Nrf2 pathway
(
Elsevier
, 2023 , Article Review)
Hemodynamic shear stress is one of the major factors that are involved in the pathogenesis of many cardiovascular diseases including atherosclerosis and abdominal aortic aneurysm (AAA), through its modulatory effect on the ...
Human and economic resources for empowerment and pregnancy-related mental health in the Arab Middle East: a systematic review
(
Springer-Verlag Wien
, 2019 , Article Review)
This systematic review synthesizes research on the influence of human and economic resources for women's empowerment on their pre- and postnatal mental health, understudied in the Arab world. We include articles using ...