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Estrogen and Bisphenol A in Hypertension
(
Springer
, 2020 , Article Review)
Purpose of Review: Cardiovascular disease (CVD) is a non-subsiding disease that remains a leading cause of morbidity and mortality. CVD has been associated with endocrine disruptors, such as bisphenol A (BPA). This review ...
Western diet aggravates neuronal insult in post-traumatic brain injury: Proposed pathways for interplay
(
Elsevier
, 2020 , Article Review)
Traumatic brain injury (TBI) is a global health burden and a major cause of disability and mortality. An early cascade of physical and structural damaging events starts immediately post-TBI. This primary injury event ...
Estrogen increases expression of vascular alpha 2C adrenoceptor through the cAMP/Epac/JNK/AP-1 pathway and potentiates cold-induced vasoconstriction
(
Elsevier
, 2020 , Article)
Cutaneous cold-induced vasoconstriction is a normal physiological reaction mediated by alpha 2C-adrenergic receptors (α2C-ARs) expressed in vascular smooth muscle cells (VSMCs). When this reaction is exaggerated, Raynaud's ...
The hypertensive potential of estrogen: An untold story
(
Elsevier
, 2020 , Article Review)
Cardiovascular disease (CVD) is the major cause of morbidity and mortality worldwide. The implication of estrogen in this disease has been extensively studied. While the vast majority of published research argue for a ...
Flavonoids in adipose tissue inflammation and atherosclerosis: One arrow, two targets
(
Portland Press Ltd
, 2020 , Article Review)
Flavonoids are polyphenolic compounds naturally occurring in fruits and vegetables, in addition to beverages such as tea and coffee. Flavonoids are emerging as potent therapeutic agents for cardiovascular as well as metabolic ...
Repurposing cilostazol for raynaud's phenomenon
(
Bentham Science Publishers
, 2021 , Other)
Raynaud's Phenomenon (RP) results from exaggerated cold-induced vasoconstriction. RP patients suffer from vasospastic attacks and compromised digital blood perfusion leading to a triple color change at the level the fingers. ...
Inflammatory basis of atherosclerosis: Modulation by sex hormones
(
Bentham Science Publishers
, 2021 , Other)
Atherosclerosis-related cardiovascular diseases (CVDs) are the leading cause of death globally. Several lines of evidence are supportive of the contributory role of vascular inflammation in atherosclerosis. Di-verse immune ...