College of Health Sciences: Recent submissions
Now showing items 181-200 of 1948
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Prevalence of SPOP and IDH Gene Mutations in Prostate Cancer in a Jordanian Population
( Springer , 2024 , Article)Speckle-type POZ (SPOP) is described as an essential tumor suppressor factor in gastric cancer, colorectal cancer, and prostate cancer (PCa). SPOP gene mutations were reported in primary human PCa. Isocitrate dehydrogenase-1 ... -
Tofersen for SOD1 amyotrophic lateral sclerosis: a systematic review and meta-analysis
( Springer-Verlag Italia s.r.l. , 2025 , Article Review)Objective: Tofersen, an antisense oligonucleotide, has recently received FDA and EMA approval for treating amyotrophic lateral sclerosis (ALS) in adults with SOD1 gene mutations. This systematic review and meta-analysis ... -
Effect of different alkaline solutions in cocoa powder alkalization: Effects on pasteurized chocolate milk
( Elsevier , 2025 , Article)Alkalization results in significant changes in the characteristic properties of cocoa products. Different alkalized cocoa powders with varying properties are obtained depending on the alkaline solution used. However, no ... -
Modification and glycation microalgae proteins by non-thermal assisted process
( Elsevier , 2025 , Article Review)Plant proteins represent a promising solution worldwide due to their low production costs and easy accessibility. Additionally, plant proteins are more environmentally sustainable. Therefore, the potential of plant proteins ... -
GATA3: Orchestrating cellular fate through differentiation and proliferation
( Elsevier , 2025 , Article Review)Cell proliferation and differentiation are two fundamental biological processes that occur in biological systems, tightly regulated by various factors such as transcription factors (TFs). Zinc finger proteins are TFs ... -
Mindray CL-900i assay: An effective assay for hepatitis B surface antigen screening with superior specificity
( Elsevier , 2025 , Article)Objectives The chemiluminescence immunoassay automated Abbott ARCHITECT hepatitis B surface antigen (HBsAg) screening assay is globally recognized for its superior sensitivity but notably low specificity. This mandates ... -
Can the prevalence of one STI serve as a predictor for another? A mathematical modeling analysis
( Elsevier , 2025 , Article)We aimed to understand to what extent knowledge of the prevalence of one sexually transmitted infection (STI) can predict the prevalence of another STI, with application for men who have sex with men (MSM). An individual-based ... -
Molecular identification and characterization of waterborne protozoa among stranded Dugong dugon
( Elsevier , 2025 , Article)The Persian Gulf hosts the second-largest population of Dugongs. The International Union for the Conservation of Nature (IUCN) lists them as Vulnerable to Extinction species. Incidental fishing, vessel strikes, environmental ... -
Syphilis infection prevalence in the Middle East and North Africa: a systematic review and meta-analysis
( Elsevier , 2024 , Article)Background: Syphilis is a sexually transmitted infection (STI) that can be prevented and effectively treated; yet it continues to be a cause of morbidity and mortality worldwide. There is a limited understanding of the ... -
Empowering nurse leaders: readiness for AI integration and the perceived benefits of predictive analytics
( BioMed Central Ltd , 2025 , Article)Introduction: Artificial Intelligence (AI) is increasingly being integrated into healthcare, particularly through predictive analytics that can enhance patient care and operational efficiency. Nursing leaders play a crucial ... -
Chapter Seven Exploring the effect of disease causing mutations in metal binding sites of human ARSA in metachromatic leukodystrophy
( Elsevier , 2024 , Book chapter)The arylsulfatase A (ARSA) gene is observed to be deficient in patients with metachromatic leukodystrophy (MLD), a type of lysosomal storage disease. MLD is a severe neurodegenerative disorder characterized by an autosomal ... -
Sociodemographic characteristics and vaping motives as potential correlates of early vaping initiation
( Frontiers Media , 2024 , Article)Background: Vaping’s popularity has particularly increased among young people, with its prevalence varying across different regions, including the Middle East. The health impacts of vaping, especially when initiated early, ... -
Ethnobotanical survey of medicinal plants used in management of breast cancers in Qatar
( Elsevier , 2025 , Article)Breast cancer is a global health concern, including in Qatar, where it impacts women significantly. The complexity of breast cancer requires diverse treatment approaches influenced by tumor characteristics and biology. ... -
Advances in Huntington’s Disease Biomarkers: A 10-Year Bibliometric Analysis and a Comprehensive Review
( MDPI , 2025 , Article Review)Neurodegenerative disorders (NDs) cause progressive neuronal loss and are a significant public health concern, with NDs projected to become the second leading global cause of death within two decades. Huntington’s disease ... -
Universal Genetic Testing for Newly Diagnosed Invasive Breast Cancer
( American Medical Association , 2024 , Article)IMPORTANCE Between 5% and 10% of breast cancer cases are associated with an inherited germline pathogenic or likely pathogenic variant (GPV) in a breast cancer susceptibility gene (BCSG), which could alter local and systemic ... -
In vivo assessment of the nephrotoxic effects of the synthetic cannabinoid AB-FUBINACA
( Springer , 2024 , Article)Background: The widespread misuse of synthetic cannabinoids (SCs) has led to a notable increase in reported adverse effects, raising significant health concerns. SCs use has been particularly associated with acute kidney ... -
Ferulic acid: extraction, estimation, bioactivity and applications for human health and food
( John Wiley and Sons Ltd , 2024 , Article Review)Ferulic acid ((E)-3-(4-hydroxy-3-methoxy-phenyl) prop-2-enoic acid) is a derivative of caffeic acid found in most plants. This abundant phenolic compound exhibits significant antioxidant capacity and a broad spectrum of ... -
The dynamic role of immune checkpoint molecules in diagnosis, prognosis, and treatment of head and neck cancers
( Elsevier , 2024 , Article Review)Head and neck cancer (HNC) is the sixth most common cancer type, accounting for approximately 277,597 deaths worldwide. Recently, the Food and Drug Administration (FDA) has approved immune checkpoint blockade (ICB) agents ... -
Determinants and prediction of hypertension among Chinese middle-aged and elderly adults with diabetes: A machine learning approach
( Elsevier , 2024 , Article)Objective: Multimorbidity, particularly diabetes combined with hypertension (DCH), is a significant public health concern. Currently, there is a gap in research utilizing machine learning (ML) algorithms to predict ... -
The effect of colchicine on myocardial infarction: An updated systematic review and meta-analysis of randomized controlled trials
( Elsevier , 2025 , Article)INTRODUCTION: Myocardial infarction (MI) is associated with a significant post-event inflammatory response which further contributes to post-MI prognosis. Colchicine, an anti-inflammatory agent, exhibits potential benefits ...
