Browsing Biomedical Sciences by Type "Article Review"
Now showing items 21-40 of 90
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Drosophila as a Model Organism in Host–Pathogen Interaction Studies
( Frontiers Media , 2020 , Article Review)Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and ... -
The Dual Specificity Role of Transcription Factor FOXO in Type 2-diabetes and Cancer
( Bentham Science Publishers , 2018 , Article Review)The FOXO (Forkhead box O) transcription factors are implicated in several signaling pathways and play a vital role in various cellular and physiological processes include for instance, ROS (reactive oxygen species) response, ... -
Effect of Resveratrol on Pregnancy, Prenatal Complications and Pregnancy-Associated Structure Alterations.
( MDPI , 2023 , Article Review)Adverse pregnancy outcomes are considered significant health risks for pregnant women and their offspring during pregnancy and throughout their lifespan. These outcomes lead to a perturbated in-utero environment that impacts ... -
Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis.
( Springer , 2020 , Article Review)Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an abnormal fibrotic response involving vast ... -
Epac in vascular smooth muscle cells
( MDPI , 2020 , Article Review)Vascular smooth muscle cells (VSMCs) are major components of blood vessels. They regulate physiological functions, such as vascular tone and blood flow. Under pathological conditions, VSMCs undergo a remodeling process ... -
Epstein-Barr virus-associated malignancies: Roles of viral oncoproteins in carcinogenesis
( Frontiers Media S.A. , 2018 , Article Review)The Epstein-Barr virus (EBV) is the first herpesvirus identified to be associated with human cancers known to infect the majority of the world population. EBV-associated malignancies are associated with a latent form of ... -
Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update
( Frontiers Medi , 2018 , Article Review)The Epstein–Barr virus (EBV) is a DNA lymphotropic herpesvirus and the causative agent of infectious mononucleosis. EBV is highly prevalent since it affects more than 90% of individuals worldwide and has been linked to ... -
Estrogen and Bisphenol A in Hypertension
( Springer , 2020 , Article Review)Purpose of Review: Cardiovascular disease (CVD) is a non-subsiding disease that remains a leading cause of morbidity and mortality. CVD has been associated with endocrine disruptors, such as bisphenol A (BPA). This review ... -
Estrogen in vascular smooth muscle cells: A friend or a foe?
( Elsevier Inc. , 2018 , Article Review)Cardiovascular disease (CVD) continues to be the leading cause of death worldwide. The effect of estrogen on these diseases has been assessed in in vitro and in vivo models, as well as in observational studies. Collectively, ... -
Evolving strategies and application of proteins and peptide therapeutics in cancer treatment
( Elsevier , 2023 , Article Review)Several proteins and peptides have therapeutic potential and can be used for cancer therapy. By binding to cell surface receptors and other indicators uniquely linked with or overexpressed on tumors compared to healthy ... -
Experimental Assessment of Cardiovascular Physiology in the Chick Embryo.
( American Association for Anatomy Journals , 2023 , Article Review)High resolution assessment of cardiac functional parameters is crucial in translational animal research. The chick embryo is a historically well-used in vivo model for cardiovascular research due to its many practical ... -
Expression profile of MicroRNA: An Emerging Hallmark of Cancer.
( Bentham Science Publishers , 2019 , Article Review)MicroRNA (miRNAs), a class of small, endogenous non-coding RNA molecules of about 21-24 nucleotides in length, have unraveled a new modulatory network of RNAs that form an additional level of post-transcriptional gene ... -
Flavonoids in adipose tissue inflammation and atherosclerosis: One arrow, two targets
( Portland Press Ltd , 2020 , Article Review)Flavonoids are polyphenolic compounds naturally occurring in fruits and vegetables, in addition to beverages such as tea and coffee. Flavonoids are emerging as potent therapeutic agents for cardiovascular as well as metabolic ... -
Forging the Path to Precision Medicine in Qatar: A Public Health Perspective on Pharmacogenomics Initiatives
( Frontiers Media , 2024 , Article Review)Pharmacogenomics (PGx) is an important component of precision medicine that promises tailored treatment approaches based on an individual’s genetic information. Exploring the initiatives in research that help to integrate ... -
The Genetic Control of the Rheumatic Heart: Closing the Genotype-Phenotype Gap
( Frontiers Media , 2021 , Article Review)Rheumatic heart disease (RHD) is a heritable inflammatory condition characterized by carditis, arthritis, and systemic disease. Although remaining neglected, the last 3 years has seen some promising advances in RHD research. ... -
Genetic epidemiology of male infertility (MI) in Arabs: a systematic review
( CSIRO , 2022 , Article Review)Although Male Infertility (MI) in Arabs is fairly common, there is a dearth in published reports of genetic epidemiology of MI among Arabs. This study aimed to review the existing literature reporting the variants that are ... -
Genetic epidemiology of Woodhouse-Sakati Syndrome in the Greater Middle East region and beyond: a systematic review
( BioMed Central Ltd , 2023 , Article Review)Background: Woodhouse-Sakati syndrome (WSS) is a rare, autosomal recessive genetic disorder with variable clinical manifestations mainly affecting the endocrine and nervous systems. The aim of this study was to systematically ... -
Genetic polymorphisms associated with obesity in the Arab world: a systematic review
( Springer Nature , 2021 , Article Review)Background: Obesity, one of the most common chronic health conditions worldwide, is a multifactorial disease caused by complex genetic and environmental interactions. Several association studies have revealed a considerable ... -
Helicobacter pylori and epithelial mesenchymal transition in human gastric cancers: An update of the literature
( Elsevier , 2023 , Article Review)Gastric cancer, a multifactorial disease, is considered one of the most common malignancies worldwide. In addition to genetic and environmental risk factors, infectious agents, such as Epstein-Barr virus (EBV) and Helicobacter ... -
Human monkeypox virus in the shadow of the COVID-19 pandemic
( Elsevier , 2023 , Article Review)Background: The end of smallpox in 1980 and the subsequent stopping of vaccination against smallpox was followed by the emergence of monkeypox (mpox), a viral disease of animal origin, meaning that it is transmitted from ...