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Waning mRNA-1273 Vaccine Effectiveness against SARS-CoV-2 Infection in Qatar

Abu-Raddad, Laith J.; Chemaitelly, Hiam; Ayoub, Houssein H.; Yassine, Hadi M.; Abdul Rahim, Hanan F.; ... more authors ... less authors ( Massachussetts Medical Society , 2022 , Other)

In early 2021, Qatar launched a mass immunization campaign with the mRNA-1273 (Moderna)1 vaccine against coronavirus disease 2019 (Covid-19).2 We assessed the persistence of real-world vaccine effectiveness against severe ...

History of primary-series and booster vaccination and protection against Omicron reinfection

Chemaitelly, Hiam; Ayoub, Houssein H.; Tang, Patrick; Coyle, Peter V.; Yassine, Hadi M.; ... more authors ... less authors ( American Association for the Advancement of Science , 2023 , Article)

Laboratory evidence suggests a possibility of immune imprinting for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We investigated the differences in the incidence of SARS-CoV-2 reinfection in a ...

Short- and longer-term all-cause mortality among SARS-CoV-2- infected individuals and the pull-forward phenomenon in Qatar: a national cohort study

Chemaitelly, Hiam; Faust, Jeremy Samuel; Krumholz, Harlan M.; Ayoub, Houssein H.; Tang, Patrick; ... more authors ... less authors ( Elsevier , 2023 , Article)

ObjectivesWe assessed short-, medium-, and long-term all-cause mortality risks after a primary SARS-CoV-2 infection. MethodsA national, matched, retrospective cohort study was conducted in Qatar to assess risk of all-cause ...

Seroprevalence of hepatitis E virus (HEV) among male craft and manual workers in Qatar (2020–2021)

Nadin, Younes; Yassine, Hadi M.; Nizamuddin, Parveen Banu; Kourentzi, Katerina; Tang, Patrick; ... more authors ... less authors ( Elsevier , 2023 , Article)

BackgroundThe rapid growth of Qatar in the last two decades has attracted a large influx of immigrant craft and manual workers (CMWs) seeking employment in jobs associated with food handling, domestic service, and construction. ...

Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar

Chemaitelly, Hiam; Ayoub, Houssein H; Faust, Jeremy Samuel; Coyle, Peter; Tang, Patrick; ... more authors ... less authors ( BMJ Publishing Group , 2023 , Article)

Objective To assess the evolution of COVID-19 severity and fatality in a unique setting that consistently applied, throughout the pandemic, rigorous and standardised criteria for defining severe COVID-19 outcomes. Methods ...

Metabolomics Approaches for the Diagnosis, Treatment, and Better Disease Management of Viral Infections

Al-Sulaiti, Haya; Almaliti, Jehad; Naman, C. B.; Al Thani, Asmaa A.; Yassine, Hadi M. ( MDPI , 2023 , Article Review)

Metabolomics is an analytical approach that involves profiling and comparing the metabolites present in biological samples. This scoping review article offers an overview of current metabolomics approaches and their ...

Comparative analysis of within-host diversity among vaccinated COVID-19 patients infected with different SARS-CoV-2 variants

Hebah A., Al-Khatib; Smatti, Maria K.; Ali, Fatma H.; Zedan, Hadeel T.; Thomas, Swapna; ... more authors ... less authors ( Elsevier , 2022 , Article)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly evolving RNA virus that mutates within hosts and exists as viral quasispecies. Here, we evaluated the within-host diversity among vaccinated and ...

Molecular epidemiology, genetic diversity, and vaccine availability of viral acute gastroenteritis in the middle East and North Africa (MENA) region

Israa, Elbashir; Aldoos, Noor F.; Mathew, Shilu; Al Thani, Asmaa A.; Emara, Mohamed M.; ... more authors ... less authors ( Elsevier , 2022 , Article)

Acute gastroenteritis is the cause of considerable mortality and morbidity worldwide, particularly among children under five years in underdeveloped countries. Most acute gastroenteritis (AGE) cases are attributed to viral ...

Vaccine evaluation and genotype characterization in children infected with rotavirus in Qatar

Mathew, Shilu; Al Khatib, Hebah A.; Al Ibrahim, Malak; Al Ansari, Khalid; Smatti, Maria K.; ... more authors ... less authors ( Springer Nature , 2023 , Article)

Background: We characterized and identified the genetic and antigenic variations of circulating rotavirus strains in comparison to used rotavirus vaccines. Methods: Rotavirus-positive samples (n = 231) were collected and ...

Screening and diagnostic testing protocols for HIV and Syphilis infections in health care setting in Qatar: Evaluation and recommendations

Nasrallah, Gheyath K.; Al-Buainain, Raniya; Younes, Nadin; Dargham, Soha R.; Al-Sadeq, Duaa W.; ... more authors ... less authors ( Public Library of Science , 2023 , Article)

Background HIV and Syphilis are common STIs, which have become a concern and burden on healthcare systems, as many infections go untreated and lead to potentially serious complications. HIV is usually diagnosed with Western ...