Search
Now showing items 1-8 of 8
Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis
(
Elsevier
, 2021 , Article)
ObjectivesCytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our objective was to perform a living systematic ...
Assessing the risk of angiotensin receptor blockers on major cardiovascular events: a systematic review and meta-analysis of randomized controlled trials.
(
BMC
, 2020 , Article)
Angiotensin receptor blockers (ARBs) are commonly used as a treatment for many cardiovascular diseases, but their safety has been called into question. The VALUE trial found an increased risk of myocardial infarction in ...
Global incidence of Necrotizing Enterocolitis: a systematic review and Meta-analysis
(
BMC
, 2020 , Article)
Background: Necrotizing Enterocolitis (NEC) is a major cause of morbidity and mortality in the Neonatal Intensive Care Unit (NICU), yet the global incidence of NEC has not been systematically evaluated. We conducted a ...
Risk of wheezing and asthma exacerbation in children treated with paracetamol versus ibuprofen: a systematic review and meta-analysis of randomised controlled trials
(
BMC
, 2020 , Article)
Background
Paracetamol and ibuprofen are the most commonly used medications for fever and pain management in children. While the efficacy appears similar with both drugs, there are contradictory findings related to adverse ...
Persistence of antibodies, boostability, and interchangeability of Japanese encephalitis vaccines: A systematic review and dose-response meta-analysis
(
Elsevier
, 2022 , Article Review)
BackgroundThe burden of Japanese encephalitis (JE) is substantial and is arguably one of the most serious viral encephalitic diseases with high case fatality and no specific treatment. JE vaccines are the only available ...
Should studies with no events in both arms be excluded in evidence synthesis?
(
Elsevier
, 2022 , Article)
ObjectivesIn safety assessment, studies with no events are a frequent occurrence when conducting meta-analyses. The current approach in meta-analysis is to exclude double-zero studies from the synthesis. In this study, we ...
Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis, first update
(
Elsevier
, 2021 , Article)
ObjectivesCytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our objective was to update the data in a living ...
Association of corticosteroids use and outcomes in COVID-19 patients: A systematic review and meta-analysis
(
Elsevier
, 2020 , Article)
BackgroundTo systematically review the literature about the association between systemic corticosteroid therapy (CST) and outcomes of COVID-19 patients. MethodsWe searched Medline, Embase, EBM Reviews, Scopus, Web of ...