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Now showing items 31-40 of 44
Editorial: Novel Targeted Therapy for Lung Cancer
(
OMICS International
, 2015 , Article)
Lung cancer accounts for about 27% of all cancer deaths and considered as the leading cause of cancer-associated death worldwide. Genotype-driven therapeutics is a standard of care for majority of subgroup of NSCLC patients ...
The Association between Serum LDL Cholesterol and Genetic Variation in Chromosomal Locus 1p13.3 among Coronary Artery Disease Patients
(
Hindawi
, 2015 , Article)
Background. Several polymorphisms of a locus on chromosome 1p13.3 have a significant effect on low-density lipoprotein cholesterol (LDL-C), atherosclerosis, and acute coronary syndrome (ACS). Methods. We aimed to investigate ...
Oxidative Stress Markers In Gestational Diabetes Mellitus
(
De Gruyter
, 2015 , Conference Paper)
Oxidative stress is typically the result of an imbalance between the reactive oxygen species (ROS) and the antioxidant. The increased production of ROS could lead into some serious physiological problems on the cell, such ...
A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
(
American Society for Biochemistry and Molecular Biology
, 2015 , Article)
Retinal hyperpermeability and subsequent macular edema is a cardinal feature of early diabetic retinopathy (DR). Here, we investigated the role of bioactive lipid metabolites, in particular 12/15-lipoxygenase (LOX)-derived ...
Pigment epithelium-derived factor inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids
(
Elsevier
, 2015 , Article)
We recently demonstrated that 12/15-lipoxygenase (LOX) derived metabolites, hydroxyeicosatetraenoic acids (HETEs), contribute to diabetic retinopathy (DR) via NADPH oxidase (NOX) and disruption of the balance in retinal ...
Reference ranges of lymphocyte subsets in healthy Qatari adults
(
Future Medicine Ltd
, 2015 , Article)
Aim: Determine reference ranges of lymphocyte subsets in healthy Qatari adults.
Patients & Methods: Blood samples (n = 150) were investigated using four colors flow
cytometery. Results: The mean percentage and absolute ...
First Study in Qatar to Reveal High Legionella Count in Cooling Towers
(
Oxford University Press - ASCP
, 2015 , Article)
Legionella is an intracellular bacterium that can cause a severe communityacquired
and nosocomial
pneumonia, known as legionnaire disease (LD). The bacterium thrives in freshwater environments,
including manmade
water ...
Evidence-Based Medicine; Climbing a Mountain for a Better Decision-Making
(
Open Access Text
, 2015 , Article)
Evidence-Based Medicine is a relatively new term used in medical sittings and Health Information Technology (HIT). It is a form of medicine that integrates practitioners’ expertise with the best available practical evidences ...
“Breakthrough Therapies” for Breast Cancer Metastasis.
(
OMICS International
, 2015 , Article)
Breast Cancer Metastasis (MBC) is an ultimate death sentence
remains a challenge for clinicians worldwide.According to the
Metastatic Breast Cancer (MBC) Awareness Network about 155,000
patients are living nowadays with ...
Human Olfactory Bulb Neural Stem Cells Expressing hNGF Restore Cognitive Deficit in Alzheimer's Disease Rat Model
(
Wiley
, 2015 , Article)
In this study, we aim to demonstrate the fate of allogenic adult human olfactory bulb neural stem/progenitor cells (OBNSC/NPCs)
transplanted into the rat hippocampus treated with ibotenic acid (IBO), a neurotoxicant ...