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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
(
American Society for Biochemistry and Molecular Biology
, 2015 , Article)
Retinal hyperpermeability and subsequent macular edema is a cardinal feature of early diabetic retinopathy (DR). Here, we investigated the role of bioactive lipid metabolites, in particular 12/15-lipoxygenase (LOX)-derived ...
Pigment epithelium-derived factor inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids
(
Elsevier
, 2015 , Article)
We recently demonstrated that 12/15-lipoxygenase (LOX) derived metabolites, hydroxyeicosatetraenoic acids (HETEs), contribute to diabetic retinopathy (DR) via NADPH oxidase (NOX) and disruption of the balance in retinal ...
Reference ranges of lymphocyte subsets in healthy Qatari adults
(
Future Medicine Ltd
, 2015 , Article)
Aim: Determine reference ranges of lymphocyte subsets in healthy Qatari adults.
Patients & Methods: Blood samples (n = 150) were investigated using four colors flow
cytometery. Results: The mean percentage and absolute ...
Evidence-Based Medicine; Climbing a Mountain for a Better Decision-Making
(
Open Access Text
, 2015 , Article)
Evidence-Based Medicine is a relatively new term used in medical sittings and Health Information Technology (HIT). It is a form of medicine that integrates practitioners’ expertise with the best available practical evidences ...
“Breakthrough Therapies” for Breast Cancer Metastasis.
(
OMICS International
, 2015 , Article)
Breast Cancer Metastasis (MBC) is an ultimate death sentence
remains a challenge for clinicians worldwide.According to the
Metastatic Breast Cancer (MBC) Awareness Network about 155,000
patients are living nowadays with ...
Leptin And Free Leptin Receptor Is Associated With Polycystic Ovary Syndrome In Young Women
(
Hindawi Publishing Corporation
, 2015 , Article)
Leptin has two forms in the circulation: free and bound forms. The soluble leptin receptor (sOB-R) circulates
in the blood and can bind to leptin. The aim of this study is to assess the concentrations of the leptin and ...