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RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR
(
Public Library of Science (PLoS)
, 2016 , Article)
Real-time or quantitative PCR (qPCR) is a useful technique that requires reliable reference genes for data normalization in gene expression analysis. Adipogenesis is among the biological processes suitable for this technique. ...
Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals
(
Nature Publishing Group
, 2016 , Article)
The liver is a key organ of metabolic homeostasis with functions that oscillate in response to food intake. Although liver and gut microbiome crosstalk has been reported, microbiome-mediated effects on peripheral circadian ...
Intestinal Parasitic Infections among Long-Term-Residents and Settled Immigrants in Qatar in the Period 2005 to 2011
(
The American Society of Tropical Medicine and Hygiene
, 2013 , Article)
Abstract. The expanding economy of Qatar in the last two decades has attracted immigrants, often from countries
with poor socio-economic levels. Many arrive with patent intestinal parasitic infections, and recent analyses ...
The Qatar Biobank: background and methods
(
BioMed Central
, 2015 , Article)
Background: The Qatar Biobank aims to collect extensive lifestyle, clinical, and biological information from up to
60,000 men and women Qatari nationals and long-term residents (individuals living in the country for ≥15 ...
Genetic relatedness and host specificity of Pseudomonas aeruginosa isolates from cystic fibrosis and non-cystic fibrosis patients
(
Dove Medical Press Limited
, 2014 , Article)
Background: Pseudomonas aeruginosa is one of the primary pathogens isolated more frequently in cystic fibrosis (CF) and it exhibits innate resistance to a wide range of antibiotics.
Purpose: We sought to determine whether ...
Associations of Vitamin D Receptor Polymorphisms with Coronary Artery Diseases
(2016 , Poster)
Background:
Previous studies have investigated the association of rs1544410, rs7975232 and rs731236 polymorphisms on vitamin D receptor gene and its impact on diseases such as cancer, diabetes and hypertension in different ...
“Breakthrough Therapies” for Breast Cancer Metastasis.
(
OMICS International
, 2015 , Article)
Breast Cancer Metastasis (MBC) is an ultimate death sentence
remains a challenge for clinicians worldwide.According to the
Metastatic Breast Cancer (MBC) Awareness Network about 155,000
patients are living nowadays with ...
New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2016 , Article)
The synthesis of new 3-cyano-2-substituted pyridines bearing various pharmacophores and functionalities at position 2 is described. The synthesized compounds were evaluated for their in vitro anti-cancer activities on five ...
Inflammogenesis of Secondary Spinal Cord Injury
(
Frontiers Media
, 2016 , Article)
Spinal cord injury (SCI) and spinal infarction lead to neurological complications and eventually to paraplegia or quadriplegia. These extremely debilitating conditions are major contributors to morbidity. Our understanding ...
The Relationship Between Leptin and PCOS
(
De Gruyter
, 2014 , Conference Paper)
Background: The ob gene produces a leptin hormone that works
as a satiety signal to the hypothalamus. Leptin may have a role in polycystic ovary syndrome (PCOS) via its role on obesity and insulin resistance.
Materials ...