عرض بسيط للتسجيلة

المؤلفSharif, Elham
المؤلفFaisal, Amal
المؤلفOsman, Amal
المؤلفRizk, Nasser
تاريخ الإتاحة2016-10-10T08:17:02Z
تاريخ النشر2014-06
اسم المنشورClinical Chemistry and Laboratory Medicine
الاقتباسSharif, Elham, Faisal, Amal, Osman, Amal, Rizk, Nasser "The Relationship Between Leptin and PCOS" Clinical Chemistry and Laboratory Medicine (CCLM). Volume 52, Issue Supplement, Endocrinology Pages s737–s789 IFCC WorldLab Istanbul 2014
معرّف المصادر الموحدhttp://hdl.handle.net/10576/4854
الملخصBackground: The ob gene produces a leptin hormone that works as a satiety signal to the hypothalamus. Leptin may have a role in polycystic ovary syndrome (PCOS) via its role on obesity and insulin resistance. Materials and Methods: A prospective, retrospectives cross- sectional study included 78 females student aged 17-25 years. The retrospective data included clinical, anthropometric and hormonal profile of each subject. Leptin concentration was measured by enzyme absorbent by BioVendor Human Leptin ELISA. Statistical analysis was performed by IBM SPSS Statistics 21.0 for Windows XP (IBM, USA). Results: leptin found to be significantly higher in those women with PCOS than in women without PCOS (p-value 0.037). Also, Overweight/Obese subjects had higher leptin level (22.85 ng/ml) than non-overweight/non-obese subjects (8.82 ng/ml) with (p-value <0.05). OW/Ob group showed higher frequency of family history of PCOS and diabetes, irregular menstrual cycle (IP) and high Ferriman-Gallwey score. Leptin is significantly correlated with insulin, testosterone, BMI, DHEAS, progesterone, FAI and PCOS. Conclusion: PCOS, overweight and obese subjects exhibit high leptin level.
اللغةen
الناشرDe Gruyter
الموضوعPolycystic Ovary Syndrome (PCOS)
Leptin
Testosterone
BMI
العنوانThe Relationship Between Leptin and PCOS
النوعConference Paper
رقم المجلد52
ESSN1437-4331
dc.accessType Open Access


الملفات في هذه التسجيلة

Thumbnail
Thumbnail

هذه التسجيلة تظهر في المجموعات التالية

عرض بسيط للتسجيلة