An International Investigation of Molar Incisor Hypomineralisation (iMIH) and Its Association with Dental Anomalies: Development of a Protocol
Date
2023-05-01Author
Rodd, Helen D.Nazzal, Hani
Bonifacio, Clarissa Calil
Ruth, Choe Wei
Crombie, Felicity
El Shahawy, Osama
Folayan, Morenike Oluwatoyin
Gambetta-Tessini, Karla
Goyal, Ashima
Hasmun, Noren
Issa, Ahmad I.
Jundi, Suhad
Manton, David J.
Narasimhan, Srinivasan
Omar, Samah
Parekh, Susan
Popoola, Bamidele O.
Silva, Mihiri
Taylor, Greig
Naomi, Yang Qiyue
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Background: Molar incisor hypomineralisation (MIH) is a common disorder of tooth development, which has recently been found to be associated with a higher prevalence of hypodontia. The aim of this international multicentre study is to determine the association between MIH and other developmental anomalies in different populations. Methods: Investigators were trained and calibrated for the assessment of MIH and dental anomalies and ethical approvals obtained in each participating country. The study aimed to recruit 584 children with MIH and 584 children without MIH. Patients aged 7–16 years who attend specialist clinics will be invited to participate. Children will undergo a clinical examination to determine the presence and severity of MIH, using an established index. The presence of any other anomalies, affecting tooth number, morphology, or position, will be documented. Panoramic radiographs will be assessed for dental anomalies and the presence of third permanent molars. Statistical analysis, using a chi squared test and regression analysis, will be performed to determine any differences in dental anomaly prevalence between the MIH and non-MIH group and to determine any association between dental anomalies and patient characteristics. Conclusion: This large-scale study has the potential to improve understanding about MIH with benefits for patient management.
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- Dental Medicine Research [296 items ]