تصفح College of Medicine حسب العنوان
السجلات المعروضة 5 -- 7 من 7
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STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
(2024 , Dissertation)Homocystinuria, a rare disorder stemming from mutations in the CBS gene, results in cystathionine β-synthase (CBS) deficiency. CBS is a pivotal enzyme whose activity is enhanced by the allosteric regulator S-adenosylmethionine ... -
VASCULAR REMODELING IN HYPERTENSION: IN-VITRO/ EX-VIVO MECHANICAL STRETCH-INDUCED ALTERATIONS AND OMICS ANALYSIS
(2024 , Dissertation)Hypertension, being a primary vasculature disorder, contributes significantly to premature death globally. Over the years, numerical figures have evidenced a dramatic increase in hypertension’s global prevalence, affecting ... -
Vitamin D Immune Modulatory Effect on the Anti-inflammatory potential of HDL Associated Proteins
(2023 , Dissertation)Introduction: Vitamin D deficiency is highly prevalent in Qatar. Vitamin D exerts immune-modulatory effects leading to reduced inflammation. Therefore, vitamin D deficiency is associated with increased subclinical inflammation. ...