Search
Now showing items 1-8 of 8
Functional In Vivo Imaging of Tumors.
(
Springer
, 2020 , Book chapter)
Noninvasive imaging of functional and molecular changes in cancer has become an indispensable tool for studying cancer in vivo. Targeting the functional and molecular changes in cancer imaging provides a platform for the ...
1H magnetic resonance spectroscopy of 2H-to-1H exchange quantifies the dynamics of cellular metabolism in vivo
(
Nature Research
, 2020 , Article)
Quantitative mapping of the in vivo dynamics of cellular metabolism via non-invasive imaging contributes to our understanding of the initiation and progression of diseases associated with dysregulated metabolic processes. ...
Brain Microstructural Changes Support Cognitive Deficits in Normal Children Born to HIVinfected Mothers
(2018 , Conference Proceedings)
Synopsis
In the current study, we evaluated the brain integrity [by mapping the fractional anisotropy (FA) and mean diffusivity (MD)] and neurocognitive
performance (NP) in normal children (NCI) born to HIV-infected ...
Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers
(
Elsevier
, 2020 , Article)
IntroductionAntiretroviral therapy (ART) is considered the most effective way to prevent perinatal transmission of human immunodeficiency virus (HIV). However, there is little knowledge about the effect of ART on the brain ...
Single-Voxel H MR spectroscopy of cerebral nicotinamide adenine dinucleotide (NAD ) in humans at 7T using a 32-channel volume coil.
(
Wiley
, 2019 , Article)
Reliable monitoring of tissue nicotinamide adenine dinucleotide (NAD ) concentration may provide insights on its roles in normal and pathological aging. In the present study, we report a H MRS pulse sequence for the in ...
Epigenetic and breast cancer therapy: Promising diagnostic and therapeutic applications.
(
Elsevier
, 2020 , Article Review)
The global burden of breast cancer (BC) is increasing significantly. This trend is caused by several factors such as late diagnosis, limited treatment options for certain BC subtypes, drug resistance which all lead to poor ...
RAS-mediated oncogenic signaling pathways in human malignancies
(
Elsevier
, 2018 , Article Review)
Abnormally activated RAS proteins are the main oncogenic driver that governs the functioning of major signaling
pathways involved in the initiation and development of human malignancies. Mutations in RAS genes and
or its ...
Role of animal research in human malignancies
(
Elsevier
, 2019 , Book chapter)
Animal models are the central backbone in relation to providing the safety information of xenobiotics, the nature of chemicals present in the environment, and understanding the developmental process in disease pathogenesis ...