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AuthorBansode, Rishipal R.
AuthorRandolph, Priscilla
AuthorAhmedna, Mohamed
AuthorWilliams, Leonard L.
AuthorYu, Jianmei
Available date2017-02-27T09:49:49Z
Publication Date2015-03
Publication NameJournal of Medicinal Food
Identifierhttp://dx.doi.org/ 10.1089/jmf.2014.0060
CitationBansode Rishipal R., Randolph Priscilla, Ahmedna Mohamed, Williams Leonard L., and Yu Jianmei. Journal of Medicinal Food. March 2015, 18(3): 265-272
ISSN1096-620X
URIhttp://hdl.handle.net/10576/5308
AbstractPeanut skin is a rich source of polyphenols, such as proanthocyanidins. Peanut skin proanthocyanidins mainly consist of a subgroup called procyanidins. Peanut-based procyanidins contain oligomers of both type A and type B procyanidins. Recent studies have shown that peanut skin extracts exert protection against hepatic steatosis induced on rats fed with a high-fat diet. Studies have shown that proanthocyanidins protect against cardiovascular diseases (CVDs). The mechanism of CVD protection and hypolipidemic effect of peanut skin procyanidins has been gradually revealed in recent years. Due to the high molecular weight of procyanidins, they are not readily absorbed through the gut barrier. It is hypothesized that procyanidins exert their effect by inhibiting the absorption of dietary lipid and chylomicron secretion by enterocytes. In this review, we aim to highlight the hypolipidemic effects of peanut skin polyphenols and discuss the various molecular mechanisms, with which the polyphenols may exert the lipid-lowering function observed by weighing the absorption characteristics as well as gene expression mechanism responsible for lipid homeostasis.
Languageen
PublisherMary Ann Liebert, Inc.
Subjecthypolipidemia
lipid metabolism
peanut skins
proanthocyanidins
TitleBioavailability and hypolipidemic effects of peanut skin polyphenols
TypeArticle
Pagination265-272
Issue Number3
Volume Number18
ESSN1557-7600


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