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AuthorAlhajj, Mohammed Nasser
AuthorHalboub, Esam
AuthorYacob, Norlela
AuthorAl-Maweri, Sadeq Ali
AuthorAhmad, Siti Fauzza
AuthorCelebić, Asja
AuthorAl-Mekhlafi, Hesham M.
AuthorSalleh, Nosizana Mohd
Available date2024-04-03T08:13:34Z
Publication Date2024-12-01
Publication NameBMC Oral Health
Identifierhttp://dx.doi.org/10.1186/s12903-024-04083-2
CitationAlhajj, M.N., Halboub, E., Yacob, N. et al. Adhesion of Candida Albicans to digital versus conventional acrylic resins: a systematic review and meta-analysis. BMC Oral Health 24, 303 (2024). https://doi.org/10.1186/s12903-024-04083-2
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85186624355&origin=inward
URIhttp://hdl.handle.net/10576/53874
AbstractBackground: The present systematic review and meta-analysis investigated the available evidence about the adherence of Candida Albicans to the digitally-fabricated acrylic resins (both milled and 3D-printed) compared to the conventional heat-polymerized acrylic resins. Methods: This study followed the guidelines of the Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA). A comprehensive search of online databases/search tools (Web of Science, Scopus, PubMed, Ovid, and Google Scholar) was conducted for all relevant studies published up until May 29, 2023. Only in-vitro studies comparing the adherence of Candida albicans to the digital and conventional acrylic resins were included. The quantitative analyses were performed using RevMan v5.3 software. Results: Fourteen studies were included, 11 of which were meta-analyzed based on Colony Forming Unit (CFU) and Optical Density (OD) outcome measures. The pooled data revealed significantly lower candida colonization on the milled digitally-fabricated compared to the heat-polymerized conventionally-fabricated acrylic resin materials (MD = − 0.36; 95%CI = − 0.69, − 0.03; P = 0.03 and MD = − 0.04; 95%CI = − 0.06, − 0.01; P = 0.0008; as measured by CFU and OD respectively). However, no differences were found in the adhesion of Candida albicans between the 3D-printed digitally-fabricated compared to the heat-polymerized conventionally-fabricated acrylic resin materials (CFU: P = 0.11, and OD: P = 0.20). Conclusion: The available evidence suggests that candida is less likely to adhere to the milled digitally-fabricated acrylic resins compared to the conventional ones.
Languageen
PublisherBMC
SubjectAcrylic resin
CAD-CAM
Candida Albicans
Digital denture
Prosthodontics
TitleAdhesion of Candida Albicans to digital versus conventional acrylic resins: a systematic review and meta-analysis
TypeArticle
Issue Number1
Volume Number24
ESSN1472-6831
dc.accessType Open Access


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