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AuthorAbdel-Hameed, Hijazi
AuthorAl-Hamed, Faez Saleh
AuthorTamimi, Faleh
AuthorAl-Maweri, Sadeq A.
AuthorHamdan, Nader
AuthorPsutka, David J.
AuthorTa, Peter
AuthorKlieb, Hagen
Available date2024-04-03T08:58:09Z
Publication Date2024-04-30
Publication NameJournal of Oral Biology and Craniofacial Research
Identifierhttp://dx.doi.org/10.1016/j.jobcr.2024.02.007
ISSN22124268
URIhttps://www.sciencedirect.com/science/article/pii/S2212426824000307
URIhttp://hdl.handle.net/10576/53876
AbstractChronic oral mucosal diseases (COMDs) represent a significant challenge for clinicians and patients. They are commonly associated with chronic pain and negative effects on healing and patient's quality of life. Regenerative medicine including the use of biological autologous blood-derived substances (e.g., platelet concentrates [PCs]), has been reported to improve healing and reduce pain in orthopedic and maxillofacial surgeries as well as chronic oral mucosal diseases. In this review, we aim to describe the different types of PCs and their applications in the management of COMDs such as lichen planus, mucositis, pemphigus vulgaris, mucous membrane pemphigoid, and plasma cell mucositis, in terms of healing potential, pain control, and quality of life. Overall, PC applications seem to enhance healing and reduce pain in patients with COMDs. However, due to the small sample size and the lack of standardized clinical trials, further research is required to support these findings.
Languageen
PublisherElsevier
SubjectPlatelet-rich plasma
Platelet-rich fibrin
Platelet concentrates
Oral lesions
Oral ulcers
TitleRegenerative potential of platelet concentrates in chronic oral mucosal lesions
TypeArticle
Pagination216-221
Issue Number2
Volume Number14
Open Access user License http://creativecommons.org/licenses/by-nc-nd/4.0/
ESSN2212-4276
dc.accessType Open Access


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