Browsing Center for Sustainable Development by Author "Mahmoudi, Asma"
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Comparative study of the effect of oleuropein and hydroxytyrosol rich extracts on the reproductive toxicity induced by bisphenol A in male rats: biochemical, histopathological, and molecular analyses
Mahmoudi, Asma; Hadrich, Fatma; Bouallagui, Zouhaier; Feki, Ines; Ghorbel, Hela; Ayadi, Lobna; Chamkha, Mohamed; Sayadi, Sami... more authors ... less authors ( Springer , 2023 , Article)Bisphenol A, or BPA, goes into the composition of a large number of products including sunglasses, infant’s feeding bottles, receipts, or food packaging. Nowadays, there is a growing evidence that BPA may be at the origin ... -
Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats
Sayadi, Sami; Mahmoudi, Asma; Daoued, Ines; Marrekchi, Rim; Ghorbel, Hela ( Hindawi , 2020 , Article)Oleuropein and hydroxytyrosol, as major compounds of olive leaves, have been reported to exert numerous pharmacological properties, including anticancer, antidiabetic, and anti-inflammatory activities. The purpose of this ... -
Contribution of major polyphenols to the antioxidant profile and cytotoxic activity of olive leaves
Bouallagui, Zouhaier; Mahmoudi, Asma; Maalej, Amina; Hadrich, Fatma; Isoda, Hiroko; Sayadi, Sami... more authors ... less authors ( Bentham Science Publishers , 2019 , Article)Aims: This study was designed to investigate the phytochemical profile and the cytotoxic activities of the eco-friendly extracts of olive leaves from Chemlali cultivar. Materials and Methods: The Phenolic composition of ... -
Hepatoprotective Effect of Oleuropein-Rich Extract from Olive Leaves against Cadmium-Induced Toxicity in Mice
Jemai, Hedya; Mahmoudi, Asma; Feryeni, Anwar; Fki, Ines; Bouallagui, Zouhaier; Choura, Sirine; Chamkha, Mohamed; Sayadi, Sami... more authors ... less authors ( Hindawi , 2020 , Article)Cadmium (Cd) is a harmful pollutant which mainly affects the liver and kidney. In this work, we investigated the hepatoprotective effects of olive leaf extract based on oleuropein against hepatic cadmium toxicity in mice. ... -
A jojoba (Simmondsia chinensis) seed cake extracts express hepatoprotective activity against paracetamol-induced toxicity in rats
Firas, Feki; Mahmoudi, Asma; Denev, Petko; Feki, Ines; Ognyanov, Manol; Georgiev, Yordan; Choura, Sirine; Chamkha, Mohamed; Trendafilova, Antoaneta; Sayadi, Sami... more authors ... less authors ( Elsevier , 2022 , Article)This study aimed to investigate the hepatoprotective activity of jojoba seed cake extracts against an acute paracetamol (PC) intoxication. Two aqueous extracts from jojoba (Simmondsia chinensis) seed cake, a simmondsin-rich ... -
Wound healing potential of quercetin-3-O-rhamnoside and myricetin-3-O-rhamnoside isolated from Pistacia lentiscus distilled leaves in rats model
Elloumi, Wiem; Mahmoudi, Asma; Ortiz, Sergio; Boutefnouchet, Sabrina; Chamkha, Mohamed; Sayadi, Sami... more authors ... less authors ( Elsevier , 2022 , Article)The development of bioproducts able to accelerate wound healing is an important topic in biomedicine. In the current study, Pistacia lentiscus distilled leaves (PDL) extract and its two isolated glycosylated flavonoids, ...