• English
    • العربية
  • العربية
  • Login
  • QU
  • QU Library
  •  Home
  • Communities & Collections
  • Help
    • Item Submission
    • Publisher policies
    • User guides
    • FAQs
  • About QSpace
    • Vision & Mission
View Item 
  •   Qatar University Digital Hub
  • Qatar University Institutional Repository
  • Academic
  • Faculty Contributions
  • QU Health
  • QU Health Research
  • View Item
  • Qatar University Digital Hub
  • Qatar University Institutional Repository
  • Academic
  • Faculty Contributions
  • QU Health
  • QU Health Research
  • View Item
  •      
  •  
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Prospective cohort study of vitamin D deficiency in pregnancy: Prevalence and limited effectiveness of 1000 IU vitamin D supplementation

    Thumbnail
    View/Open
    abdelmageed-et-al-2024-prospective-cohort-study-of-vitamin-d-deficiency-in-pregnancy-prevalence-and-limited.pdf (160.4Kb)
    Date
    2024-01-28
    Author
    Abdelmageed, Rasha Mohammed
    Hussein, Suha Majeed Mohammed
    Anamangadan, Shamil Mohamed
    Abdullah, Rola Walid Mahmoud
    Rauf, Lubna
    AlFehaidi, Al Anoud Saleh
    Hamed, Ehab
    ...show more authors ...show less authors
    Metadata
    Show full item record
    Abstract
    Background: Vitamin D deficiency is highly prevalent worldwide among pregnant women. Although vitamin D supplementation is effective in improving vitamin D status, the safety and optimal dosing of vitamin D supplementation during pregnancy remain less well understood. Objective: This study aimed to investigate the prevalence of vitamin D deficiency among pregnant women and evaluate the effectiveness of vitamin D supplementation in improving vitamin D status during pregnancy. Design: This prospective cohort study assessed the impact of a 16-week daily vitamin D supplementation 1000 IU regimen on vitamin D status among pregnant women. Methods: A total of 365 pregnant women were recruited, and their baseline total circulating 25-hydroxy vitamin D concentrations were measured. Of these, 249 participants completed the study, which involved oral daily supplementation with 1000 IU of vitamin D and a repeat of total circulating 25-hydroxy vitamin D concentrations after 16 weeks. Results: The study found that 57.7% of the participants had vitamin D deficiency, consistent with the rates reported in other studies. However, vitamin D supplementation at a dose of 1000 IU had a small effect size and was not clinically significant. However, 67% of participants with vitamin D deficiency remained deficient; among participants initially with vitamin D insufficiency, 30% became deficient. Moreover, 26.5% of individuals with sufficient vitamin D status at 12 weeks showed insufficient levels by 28 weeks. Conclusion: Vitamin D deficiency is widespread among pregnant women, and vitamin D supplementation at a daily dose of 1000 IU may not adequately address this problem. Although the study has limitations, its results align with previous research and may apply to other populations with a high prevalence of vitamin D deficiency during pregnancy. Further research is necessary to determine the most effective approach for addressing prenatal vitamin D deficiency.
    URI
    https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85183617846&origin=inward
    DOI/handle
    http://dx.doi.org/10.1177/17455057231222404
    http://hdl.handle.net/10576/54543
    Collections
    • QU Health Research [‎110‎ items ]

    entitlement

    Related items

    Showing items related by title, author, creator and subject.

    • Thumbnail

      25-Hydroxyvitamin D Concentrations and Clostridium difficile Infection: A Meta-Analysis 

      Furuya-Kanamori, L.; Wangdi, K.; Yakob, L.; McKenzie, S.J.; Doi, S.A.R.; Clark, J.; Paterson, D.L.; Riley, T.V.; Clements, A.C.A.... more authors ... less authors ( SAGE Publications Inc. , 2017 , Article)
      Background: Well-known risk factors for Clostridium difficile infection (CDI) are exposure to antibiotics and gastric acid suppressants. Recent studies have provided some evidence of an association between hypovitaminosis ...
    • Thumbnail

      Reply to "Double-counting of effect sizes and inappropriate exclusion of studies in "The influence of vitamin D supplementation on IGF-1 levels in humans: A systematic review and meta_analysis" 

      Kord-Varkaneh, Hamed; Rinaldi, Giulia; Hekmatdoost, Azita; Fatahi, Somaye; Tan, Shing Cheng; Shadnoush, Mahdi; Khni, Vahid; Mousavi, Seyed Mohammad; Zarezadeh, Meysam; Salamat, Shekoufeh; Bawadi, Hiba; Rahmani, Jamal... more authors ... less authors ( Elsevier , 2021 , Other)
      Dear Editor, We appreciate the comments provided to us in the letter from Amiri et al. We would like to offer some clarifications in response to the comments. Firstly, the authors claimed that we included the control ...
    • Thumbnail

      Association of Blood Levels of Vitamin D and Its Binding Protein with Clinical Phenotypes of Multiple Sclerosis. 

      Al-Shammri, Suhail; Chattopadhyay, Arpita; Hanah, Magdy Girgis; Doi, Suhail; Akanji, Abayomi ( MDPI , 2023 , Article)
      Low vitamin D levels may synergize with changing levels of the vitamin D binding protein (DBP) to precipitate in the development and clinical progression of multiple sclerosis (MS). In this study, this hypothesis was ...

    Qatar University Digital Hub is a digital collection operated and maintained by the Qatar University Library and supported by the ITS department

    Contact Us | Send Feedback
    Contact Us | Send Feedback | QU

     

     

    Home

    Submit your QU affiliated work

    Browse

    All of Digital Hub
      Communities & Collections Publication Date Author Title Subject Type Language Publisher
    This Collection
      Publication Date Author Title Subject Type Language Publisher

    My Account

    Login

    Statistics

    View Usage Statistics

    About QSpace

    Vision & Mission

    Help

    Item Submission Publisher policiesUser guides FAQs

    Qatar University Digital Hub is a digital collection operated and maintained by the Qatar University Library and supported by the ITS department

    Contact Us | Send Feedback
    Contact Us | Send Feedback | QU

     

     

    Video