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AuthorKhan, Adnan M.
AuthorMohammed, Aisha F.
AuthorAl-Hajri, Shama A.
AuthorShamari, Hajer M. Al
AuthorQidwai, Uvais
AuthorMujeeb, Imaad
AuthorRajpoot, Nasir M.
Available date2024-05-07T05:39:58Z
Publication Date2014
Publication NameMiddle East Conference on Biomedical Engineering, MECBME
ResourceScopus
Identifierhttp://dx.doi.org/10.1109/MECBME.2014.6783229
ISSN21654247
URIhttp://hdl.handle.net/10576/54687
AbstractGrading of breast cancer is often done by an expert pathologist based on their analysis of micro-level structural features of the cancerous tissue specimen as well as the level of presence of certain protein molecules in the specimen. The process of assessment of the level of presence of estrogen and progesterone receptors molecules is subjective by its very nature and therefore, causes large inter-expert and sometimes even intra-expert variability, potentially adding noise to the process of selecting the treatment regime for the patient. Quantification of immunohistochemical stains is critical for an objective assessment of breast cancer histopathology specimens. We present a fast, compact and inexpensive system for scoring the Estrogen and Progesterone hormone receptors in breast cancer histopathology slides using image analysis algorithm. We describe hardware and software issues in the construction of the system, and present a comparison of scores produced by our system to those produced by many expert pathologists.
Languageen
PublisherIEEE
SubjectBiomedical engineering
Endocrinology
Grading
Molecules
Patient treatment
Cancerous tissues
Hardware and software
Hormone receptors
Image analysis algorithms
Objective assessment
Progesterone receptor
Protein molecules
Structural feature
Diseases
TitleA novel system for scoring of hormone receptors in breast cancer histopathology slides
TypeConference Paper
Pagination155-158
dc.accessType Abstract Only


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