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المؤلفMekonnen, Tefera Chane
المؤلفMelaku, Yohannes Adama
المؤلفShi, Zumin
المؤلفGill, Tiffany K.
تاريخ الإتاحة2024-05-09T10:53:42Z
تاريخ النشر2024-02-28
اسم المنشورEuropean Journal of Nutrition
المعرّفhttp://dx.doi.org/10.1007/s00394-024-03356-4
الاقتباسMekonnen, T. C., Melaku, Y. A., Shi, Z., & Gill, T. K. (2024). Ultra-processed food consumption and risk of chronic respiratory diseases mortality among adults: evidence from a prospective cohort study. European Journal of Nutrition, 1-16.
الرقم المعياري الدولي للكتاب1436-6207
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85186255802&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/54793
الملخصPurpose: The purpose of the study was to determine the relationships between ultra-processed food (UPF) consumption and risk of mortality due to chronic respiratory diseases (CRDs) overall, chronic obstructive pulmonary disease (COPD), and lung cancer. Methods: A total of 96,607 participants aged 55 years and over were included from the Prostate, Lung, Colorectal and Ovarian (PLCO) cancer trial. Dietary intake was measured using food frequency questionnaire. Cox regression was fitted to estimate the risk of all-cause mortality and mortality due to CRDs overall, COPD and lung cancer associated with UPF intake. Competing risk regression was used to account for deaths from other causes and censoring. Results: During the follow-up of 1,379,655.5 person-years (median 16.8 years), 28,700 all-cause, 4092 CRDs, 2015 lung cancer and 1,536 COPD mortality occurred. A higher intake of UPF increased the risk of mortality from CRDs overall by 10% (HR 1.10; 95% CI 1.01, 1.22) and COPD by 26% (HR 1.26; 95% CI 1.06, 1.49) but not associated with lung cancer mortality risk (HR 0.97; 95% CI 0.84, 1.12). However, the risk of lung cancer increased by 16% (HR 1.16; 95% CI 1.01, 1.34) in the highest UPF intake after multiple imputation. Dose–response relationships existed for CRDs and COPD mortality but not lung cancer. Conclusion: UPF consumption was associated with an increased risk of CRD mortality. The association between UPF consumption and lung cancer mortality is inconclusive and only significant when multiple imputation was applied.
راعي المشروعThis work is supported by the Australian Government Research Training Program Scholarship.
اللغةen
الناشرDietrich Steinkopff Verlag
الموضوعAdults
COPD
Lung cancer
Mortality
Overall CRDs
Ultra-processed food
العنوانUltra-processed food consumption and risk of chronic respiratory diseases mortality among adults: evidence from a prospective cohort study
النوعArticle
الصفحات1-16
ESSN1436-6215
dc.accessType Open Access


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